中国实用儿科杂志

中国实用儿科杂志 ›› 2025, Vol. 40 ›› Issue (3): 202-211.DOI: 10.19538/j.ek2025030604

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儿童扩张型心肌病诊断和治疗的新挑战

  

  1. 1.青岛市妇女儿童医院心脏中心，山东  青岛  266034；2.重庆医科大学附属儿童医院心内科，重庆  400014；3.首都医科大学附属北京安贞医院儿科心内科，北京  100029
  • 出版日期:2025-03-06 发布日期:2025-04-17
  • 通讯作者: 韩玲，电子信箱：hanl6610@sina.com
  • 基金资助:
    青岛市临床重点攀峰学科基金（青卫政字［2022］6号）

New challenges in the diagnosis and treatment of dilated cardiomyopathy in children

  1. *Heart Center，Qingdao Women and Children′s Hospital，Qingdao  266034，China
  • Online:2025-03-06 Published:2025-04-17

摘要： 扩张型心肌病（dilated cardiomyopathy，DCM）是儿童最常见的心肌疾病，也是儿童慢性心力衰竭致死和儿童心脏移植的主要原因。儿童 DCM 病因具有高度异质性，以明确病因为目标的精准诊断面临着巨大的挑战；同时，儿童DCM治疗的前瞻性和随机对照临床研究极其少见，儿童 DCM规范的家系管理和遗传咨询亟需制定或完善基于循证证据的指南。

关键词: 扩张型心肌病, 诊断, 治疗, 儿童

Abstract: Dilated cardiomyopathy （DCM） is the most common myocardial disease in children， and is also the leading cause of death in children with chronic heart failure and of children receiving heart transplantation. The etiology of DCM in children is highly heterogeneous， and precise diagnosis with the goal of clarifying the etiology faces huge challenges; Meanwhile， prospective and randomized controlled clinical studies on the treatment of pediatric DCM are extremely rare， and there is an urgent need to develop or improve evidence-based guidelines for standardized familial management and genetic counseling of pediatric DCM.

Key words: dilated cardiomyopathy, diagnosis, treatment, child