中国实用儿科杂志

中国实用儿科杂志 ›› 2024, Vol. 39 ›› Issue (4): 311-315.DOI: 10.19538/j.ek2024040615

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重复经颅磁刺激对孤独症谱系障碍患儿的影响研究进展

  

  1. 电子科技大学医学院附属妇女儿童医院  成都市妇女儿童中心医院康复科，四川  成都  611731
  • 出版日期:2024-04-06 发布日期:2024-05-09
  • 通讯作者: 李雪，电子信箱：lixue09210822@163.com

Effect of repetitive transcranial magnetic stimulation on children with autism spectrum disorder

  1. Chengdu Women and Children's Central Hospital，School of Medicine，University of Electronic Science and Technology of China，Chengdu  611731，China
  • Online:2024-04-06 Published:2024-05-09

摘要： 孤独症谱系障碍（ASD）是一种复杂的神经发育障碍，其特征是持续的社会交往和互动缺陷以及重复刻板的行为、兴趣和活动。重复经颅磁刺激（rTMS）是一种非侵入性脑刺激，涉及到用一系列的磁脉冲刺激大脑皮质，增强或抑制皮质兴奋性，从而作为某些神经和精神疾病的一种治疗手段。文章简要回顾重复经颅磁刺激对孤独症谱系障碍患儿影响的证据，阐述重度经颅磁刺激参数和目标的选择、症状改善情况以及不良事件的产生，提出使用rTMS治疗孤独症谱系障碍患儿的可行性及潜力。

关键词: 重复经颅磁刺激, 孤独症谱系障碍, 治疗

Abstract: Autism spectrum disorder （ASD） is a complex neurodevelopmental disorder characterized by persistent deficits in social communication and interaction， as well as repetitive and stereotyped behaviors， interests and activities. Repetitive transcranial magnetic stimulation （rTMS） is a non-invasive brain stimulation involving the stimulation of the cerebral cortex with a series of magnetic pulses to enhance or inhibit cortical excitability， thereby serving as a treatment for certain neurological and psychiatric disorders. This paper briefly reviews the evidence for the effects of repetitive transcranial magnetic stimulation on children with autism spectrum disorder， describes the selection of rTMS parameters and targets， the improvement of symptoms， and the occurrence of adverse events， and proposes the feasibility and potential of using rTMS to treat children with autism spectrum disorder.

Key words: repetitive transcranial magnetic stimulation, autism spectrum disorder, treatment