关键词: 利多卡因, 下牙槽神经阻滞麻醉术, 根管治疗, 术后疼痛, 维吾尔族

Abstract:

Objective    To compare the different effect of lidocaine on reducing the postoperative pain as inferior alveolar nerve block anesthesia solution between Han and Uygur patients in first or second mandibular molar with irreversible pulpitis after single-visit root canal treatment，in order to provide a better basis for personalized clinical administration.Methods    In this clinical controlled experiments，30 Han and 30 Uygur patients were selected，whose first or second mandibular molar was diagnosed with irreversible pulpitis，and received 2% lidocaine with 1：80 000 epinephrine as the anesthetic solutions for inferior alveolar nerve blocks before single-visit root canal treatment. Each patient was asked to record their pain score on a visual analogue scale（VAS）at 6，12，24 and 48 hours after treatment. Patients were instructed that they could use analgesics（ibuprofen 300mg，Xiehe Pharmaceutical Co. Ltd.，every 6 hours）if they felt intolerable pain. Data were analyzed by Mann-Whitney test，χ2 test，Cochrane Q and T tests as well as Pearson correlation analysis. Results    The experimental data showed that postoperative pain scores of the Han patients were significantly lower than Uygur patients′scores（P＜0.05）at 6 ~12 h after single-visit root canal treatment. The use of analgesia drug in Han patients was also less than Uygur patients（P＜0.05）. Conclusion    Han patients who receive lidocaine as anesthetic solution before single-visit root canal treatment for irreversible pulpitis in first or second mandibular molars have significantly less postoperative pain and use fewer analgesics than Uygur patients.

Key words: lidocaine；inferior alveolar nerve block anesthesia；root canal treatment； , postoperative pain；Uygur