关键词: 唾液酸, 唾液酸酶, 细菌, 生存, 致病性

Abstract:

Sialic acid is a nine-carbon sugar acid，which is located at the terminal residue of glycoconjugations. The sialic acid-containing glycoconjugates are widely distributed on the surface of eukaryotic and prokaryotic cells and in serum and saliva. The sialic acid plays an important role in bacteria survival and pathogenesis. Some pathogenic bacteria coat themselves in sialic acid，providing resistance to components of host’s immune response，and some can use it as a nutrition. In this paper，the role of sialic acid and sialidase in bacteria survival and pathogen was reviewed.

Key words: sialic acid, sialidase, bacteria, survival, pathogenesis