中国实用儿科杂志

中国实用儿科杂志 ›› 2022, Vol. 37 ›› Issue (1): 29-33.DOI: 10.19538/j.ek2022010607

• 专题笔谈 • 上一篇    下一篇

儿童IgA血管炎肾损伤治疗

  

  1. 国家儿童医学中心  首都医科大学附属北京儿童医院肾病二科  儿童慢性肾脏病与血液净化北京市重点实验室，北京  100045 
  • 出版日期:2022-01-06 发布日期:2022-02-19
  • 通讯作者: 王辉，电子信箱：wanghui@bch.com.cn

Treatment for renal damage in children with IgA vasculitis

  1.  Department of Nephrology，Beijing Children’s Hospital，Capital Medical University，Beijing Key Laboratory of Pediatric Chronic Kidney Disease and Blood purification in Childhood，Beijing  100045，China
  • Online:2022-01-06 Published:2022-02-19

摘要： IgA血管炎肾损伤是IgA血管炎最为严重的并发症，与IgA血管炎病程和远期预后密切相关。目前国内外对于IgA血管炎肾损伤的治疗尚缺乏统一结论，随着国内外指南更新，对于激素及其他免疫抑制剂应用较前更为积极。文章对目前IgA血管炎肾损伤的治疗做一综述，也期望未来在儿童IgA血管炎肾损伤方面有更多高质量大样本随机对照试验为临床诊疗提供更多循证学依据。 

关键词: IgA血管炎相关肾炎, 肾损伤, 儿童, 治疗 ,

Abstract:

renal damage is the most serious complication of IgA vasculitis，which is closely related to the course and long-term prognosis for IgA vasculitis. At present，there is still no unified conclusion on the treatment of IgA vasculitis renal involvement at home and abroad. The application of glucocorticoidand immunosuppressants is more active in updated tuidelines. In this artical，the current treatment for IgAVN is reviewed，and it is expected that there will be more affirmative-quality large-sample randomized controlled trials on IgA vasculitis renal involvement in children in the future to provide more evidence-based evidence for clinical diagnosis and treatment.

Key words: IgA vasculitis nephritis, rend domage, children, treatment