关键词: 炎症, 营养, 新辅助化疗, 胃癌

Abstract: Research progress of inflammatory and nutritional indicators in evaluating the efficacy and prognosis of neoadjuvant chemotherapy for gastric cancer        CHENG Ze-wei, LIANG Yi-ze, YAN Zhi-bo, et al. Department of General Surgery, Qilu Hospital of Shandong University, Jinan 250012, China 
Corresponding author: YU Wen-bin, E- mail:wenbin_yu2003@163.com
Abstract    Neoadjuvant chemotherapy has become an essential component of the comprehensive treatment of locally advanced gastric cancer, and it is particularly important to evaluate the efficacy and prognosis of neoadjuvant chemotherapy. Inflammatory and nutritional status is not only related to the occurrence and progression of gastric cancer but also closely related to the efficacy and prognosis of neoadjuvant chemotherapy. The acquisition of inflammatory and nutritional indicators is simple and rapid, and the value of inflammatory and nutritional indicators and their changes before and after neoadjuvant therapy are closely related to tumor regression grade,disease-free survival, overall survival, and so on. The prediction model of prognosis of patients with gastric cancer after neoadjuvant chemotherapy based on inflammatory and nutritional indicators and other clinical and pathological characteristics also showed brilliant performance. The peripheral blood inflammatory and nutritional indicators are expected to become reliable indexes to evaluate the efficacy and prognosis of neoadjuvant chemotherapy for gastric cancer and have a broad clinical application prospect.

Key words: inflammation, nutrition, neoadjuvant chemotherapy, gastric cancer