关键词: 局部进展期甲状腺癌, 分化型甲状腺癌, 放射性碘治疗, 分子特征, 摄碘性

Abstract: The role of radioiodine in treatment of locally advanced differentiated thyroid cancer        LIN Yan-song*, ZHANG Teng. *Department of Nuclear Medicine, Peking Union Medical College Hospital, Beijing 100730，China
Corresponding author: LIN Yan-song，E-mail: linys@pumch.cn
Abstract    Differentiated thyroid cancer (DTC) generally has a good prognosis and a low risk of death. Thus, the management mainly focuses on the prevention and proper treatment of recurrent diseases. As an important auxiliary method for DTC diagnosis and treatment, radioiodine plays a unique role in recurrent diseases. Recently， along with the increasing of studies on treatment concept, therapeutic purpose, postoperative evaluation, the relationship between molecular characteristics and （radioiodine therapy, RAI） avidity of locally advanced DTC, more theoretical bases have been provided for enhance the comprehensive curative effect and improve patients’ prognosis and quality of life. 

Key words: locally advanced thyroid cancer, differentiated thyroid cancer, radioiodine therapy, molecular characteristics, radioiodine avidity