中国实用外科杂志

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基于临床研究科学评价减重与代谢外科新术式

张忠涛,张    鹏   

  1. 首都医科大学附属北京友谊医院普外科中心减重与代谢外科,北京 100050
  • 出版日期:2023-05-01

  • Online:2023-05-01

摘要: 减重与代谢外科在我国正处于快速发展的阶段,除手术量迅猛增加外,手术方式也呈现百花齐放的态势。我国减重与代谢外科目前开展的手术方式与国际相比有所差别,表现为全球范围内施行量最大的胃袖状切除术(SG)在我国所占比例过高、国外鲜少施行的胃袖状切除术联合空肠-空肠旁路术(SG-JJB)的数量在我国跃居第二位。由于我国减重与代谢外科发展晚于西方国家,至目前为止,整个学科所积累的高级别临床证据依然有限,所以现阶段仍应以SG和Roux-en-Y胃旁路术(RYGB)为标准推荐,其他手术不急于推广,而应以研究探索的态度开展,一方面收集完善的真实世界临床数据,另一方面鼓励开展与标准术式对比的多中心临床研究,以确定新术式的安全性、有效性及其优劣势,为客观科学评价该术式提供可靠的临床证据。

关键词:  , 肥胖, 减重与代谢手术, 评价

Abstract: Assessment and promotion of new procedures in metabolic and bariatric surgery based upon clinical research        ZHANG Zhong-tao, ZHANG Peng. Division of Metabolic and Bariatric Surgery, General Surgery Center, Beijing Friendship Hospital, Capital Medical University Beijing 100050, China
Corresponding author: ZHANG Zhong-tao, E-mail: Zhangzht@
ccmu.edu.cn
Abstract    Metabolic and bariatric surgery are in a rapid development stage in China. In addition to the sharp increase in surgical volume, different surgical procedures are also emerging. The current surgical procedures in the metabolic and bariatric surgery field in China differ from those in the international community, including that the occupation of globally most commonly performed sleeve gastrectomy (SG)  is  exceptionally high in China, and the number of globally rarely performed sleeve gastrectomy with jejunal-jejunal bypass (SG-JJB) ranks the 2nd in China. Compared to the Western world, the history of metabolic and bariatric surgery in China is not long enough. And as a result, the accumulated clinical evidence is still insufficient. Therefore, SG and Roux-en-Y gastric bypass should still be the first-line procedures and recommended as standard currently. All other bariatric procedures should be conducted as investigational and not be eager to promote. Simultaneously, integrated real-world clinical data collection from these procedures as well as multicentric clinical trials comparing new procedures versus standard procedures should be strongly recommended, in order to validate the safety, effectiveness, pros, and cons of new procedures. These endeavors will provide solid evidence that should be critical for the objective and scientific assessment of new procedures.

Key words: obesity, metabolic and bariatric surgery, assessment