中国实用外科杂志 ›› 2011, Vol. 31 ›› Issue (12): 1067-1068.

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重视和规范血管外科疾病药物治疗

吴庆华   

  1. 首都医科大学附属北京安贞医院血管外科,北京100029
  • 出版日期:2011-12-01 发布日期:2011-11-28

  • Online:2011-12-01 Published:2011-11-28

摘要:

药物治疗血管外科疾病具有与手术和腔内治疗同样的重要作用。相对于冠心病和脑血管疾病,血管外科医师多不注重外周动脉疾病病人的动脉硬化危险因素的治疗。除了治疗肢体病变,血管外科医师也应积极防治危险因素(包括抗血小板、降脂、控制血糖和血压等),因为这些病人有很高的心脑血管事件和死亡的发生率。研究表明抗血小板治疗有助于预防支架和移植物血栓形成,至少3个月的抗凝治疗有助于减少静脉血栓栓塞症的复发。在国内还缺乏对于药物治疗的临床研究,因此药物治疗还具有争议。重视临床研究以制定相关指南,重视药物的规范化使用有助于提高疗效。

关键词: 药物治疗, 外周血管疾病

Abstract:

Pay more attention to and standardize drug therapy for vascular diseases        WU Qing-hua. Department of Vascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing100029, China
Abstract    Drug therapy plays an important role in the treatment for vascular diseases just as the same as surgical and endovascular treatment. Vascular surgeons are found to treat atherosclerotic risk factors less diligently in patients with peripheral arterial disease than in patients with coronary arterial diseases or cerebral arterial diseases. In addition to therapies directed at treatment of limb symptoms, vascular surgeons should treat risk factors because patients are at very high risk for future cardiovascular events and mortality including antiplatelet therapy, lipid-lowering therapy, control of diabetic mellitus and high blood pressure. Study demonstrated antiplatelet treatment is effective in preventing thrombosis of stents or grafts. Most of trials showed duration of anticoagulation for venous thromboembolism should be at least three months. Insufficent anticoagulation time may result in higher incidence of reoccurrence. Because of a paucity of trials, the standard of drug therapy is often controversial in China. It should emphasize on clinical trials to establish guideline for drug therapy in China. Vascular surgeons often neglect comprehensive drug therapy. Paying more attention to standardization of drug therapy will improve the results of treatment.

Key words: drug therapy, peripheral vascular diseases