关键词: 表观遗传, 分子靶向治疗

Abstract:

Epigenetic inheritance of cancer and molecular targeted therapy     SHAO Jiang-hua, WANG Kai. Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Nanchang University，Nanchang 330006，China
Corresponding  author：SHAO Jiang-hua，E-mail: shao5022@163.com
Abstract    There are two epigenetic modification mechanisms，including DNA methylation and histone modification. Epigenetic  modification abnormalities can cause tumors. Studies of the mechanisms of epigenetic regulation and its reversibility have resulted in the identification of novel targets that may be useful in developing new strategieed for the molecular targets treatment of cancer.

Key words: epigenetic inheritance, molecular targeted therapy