关键词: 靶向治疗, 肿瘤, 不良反应

Abstract:

Adverse effects of tumor targeted therapies        CHEN Shan-shan，FENG Feng-yi. Chinese Academy of Medical Sciences Cancer Hospital, Peking Union Medical College,Beijing 100210, China
Corresponding  author：FENG Feng-yi ，E-mail：ffy43210@yahoo.com.cn
Abstract    Great advances have been achieved in the field of tumor targeted therapies in the last few years. Hypertension is a vascular endothelial growth factor inhibitor common side effects, and trastuzumab major adverse cardiac toxicity. Other adverse reactions are bleeding, delayed wound healing, gastrointestinal perforation, skin adverse reactions, hand-foot syndrome and mucositis, diarrhea, proteinuria. Thrombosis and reversible posterior leukoencephalopathy syndrome are rare but very serious. Early and rapid diagnosis, timely withdrawal are the keys to determine patient prognosis.

Key words:  , targeted therapy；tumor；adverse effect