中国实用外科杂志 ›› 2012, Vol. 32 ›› Issue (10): 821-824.
• 专题笔谈 • 上一篇 下一篇
高恒军,陈敏山
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摘要:
手术切除是肝细胞性肝癌主要的根治性治疗手段,术后复发是影响病人长期生存的主要因素。术后复发的非手术治疗目前选择较多,局部消融对于病灶较小的复发病灶疗效较好;而多发病灶、肿瘤直径较大且肝功能不能耐受手术的复发性肝癌,肝动脉血管介入治疗对其有很好疗效。放射治疗及分子靶向药物等治疗目前仍在研究证实其效果,多种治疗手段的联合以及针对不同复发肿瘤的特点选择不同治疗方式可以显著提高治疗效果。
关键词: 肝细胞癌, 术后复发, 非手术治疗
Abstract:
Option and clinical evaluation of non-surgical therapy of recurrent hepatocellular carcinoma after hepatectomy GAO Heng-jun, CHEN Min-shan. Department of Hepatobiliary, Sun Yat-sen University Cancer Center,Guangzhou 510060,China Corresponding author:CHEN Min-shan, E-mail:Chminsh@mail.sysu.edu.cn Abstract Surgical resection is mainly radical treatment for hepatocellular carcinoma (HCC). Recurrence after hepatectomy is a major factor induced patients’ death. Non-surgical strategies for recurrent HCC have been applied widely in clinical practice. Local ablation may be a better choice for recurrent small lesion; and as for the multiple lesions, large tumor and poor liver function could not tolerate surgery for recurrent HCC, and transarterial interventional treatment could get the satisfactory effectiveness. The effect of radiotherapy and molecular targeted drugs are uncertain for recurrent HCC. Combined treatment and selecting different therapies according to recurrent tumor characteristics could improve the therapeutic effect significantly.
Key words: hepatocellular carcinoma, postoperative recurrence, non-surgical therapy
高恒军,陈敏山. 肝癌术后复发非手术治疗方法选择及其评价[J]. 中国实用外科杂志, 2012, 32(10): 821-824.
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