中国实用外科杂志 ›› 2012, Vol. 32 ›› Issue (10): 805-808.
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蔡秀军,朱玲华
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原发性肝癌合并门静脉癌栓的治疗是肝癌治疗的难点之一,手术率低,肿瘤切除及癌栓取除手术后高复发率是影响病人长期生存的主要原因。文章介绍目前门静脉癌栓的生物学特性认识与分型研究、手术治疗方式,介绍有效地预防肝癌合门静脉癌栓术后复发的主要方法包括介入放射治疗(经门静脉灌注化疗和经肝动脉栓塞化疗)、放射治疗、125I粒子植入内放射治疗、靶向药物治疗以及免疫治疗等抗复发措施。
关键词: 肝肿瘤, 门静脉癌栓, 术后复发
Abstract:
Postoperative anti-recurrence strategies of primary liver cancer with portal vein tumor thrombus CAI Xiu-jun, ZHU Ling-hua. Department of General Surgery, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China Corresponding author: CAI Xiu-jun, E-mail: cxjzu@hotmail.com Abstract There is difficulty in effective treatment for primary liver cancer with portal vein tumor thrombus (PVTT). Low resection rate and high postoperative recurrence rate are the main problems that affect the result of surgical resection and thrombectomy for primary liver cancer with PVTT. Classification of PVTT is useful to judge the prognosis of primary liver cancer with PVTT and guide the clinical management. Based on preoperative indications and correct surgical treatment, the combination anti-recurrence managements including radioactive interventional therapy, systemic chemotherapy, radiotherapy, 125I seed implantation therapy, molecular targeted therapy and immunotherapy are useful to improve the therapeutic effect.
Key words: liver tumor, portal vein tumor thrombus, post operative recurrence
蔡秀军,朱玲华. 原发性肝癌合并门静脉癌栓术后抗复发策略[J]. 中国实用外科杂志, 2012, 32(10): 805-808.
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