关键词: 脓毒症, 液体复苏, 器官支持

Abstract:

Fluid resuscitation and organ support in sepsis        GUAN Xiang-dong, CHEN Min-ying. Intensive Care Unit, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
Corresponding author: GUAN Xiang-dong，E-mail：carlg@163.net
Abstract    Multiple organ dysfunction is the main lethal factor for septic patients. Early fluid resuscitation is the most important treatment protocol. Fluid resuscitation strategy in different period may influence organ function. Salvage resuscitation is lifesaving in septic shock period. Then, it needs optimization focus on organ rescue, optimizing and maintaining tissue perfusion, stabilization focus on organ support, aiming for zero or negative fluid balance, de-escalation focus on organ recovery, mobilizing fluid accumulated. Crystalloid or colloid don’t influence clinical outcome, maybe colloid contribute to the onset time of resuscitation. Mechanical colloid show higher acute kidney injury than albumin. Balanced salt solution contributes to less kidney injury and environment stable. 

Key words: sepsis, fluid resuscitation, organ support