关键词: 乳腺外科, 根治性手术, 规范化诊治

Abstract: Key issues of radical surgery for breast cancer        LIU Yin-hua,ZHOU Si-cheng, XIANG Hong-yu, et al. Department of Thyroid and Breast Surgery, Peking University First Hospital, Beijing 100034,China
Corresponding author：XIN Ling，E-mail:07453@pkufh.com
Abstract    In 1894，Halsted described radical mastectomy could improve 5-year survival of patients with breast cancer to 40% operation by removal of breast，axillary lymph nodes and both pectoralis muscles.For the later 130 years，Halsted radical mastectomy had been recorded in the history of breast surgery as a classical radical operation. In 1970 s，modified radical mastectomy of Patey or Auchincloss，which improved the quality of patients’life，was proved no inferior to Halsted radical mastectomy in survival benefits，and became the most common procedure implemented for more than 70% patients with breast cancer in China.Since the beginning of 21st century，with the renewal of the concept of diagnosis and treatment of breast cancer，breast conserving-surgery combined with radiotherapy，omitting axillary lymph node dissection if sentinel lymph node is negative，have been widely recognized for their clinical benefits.The concept of radical surgery for breast cancer has been updated.Scientific interpretation of radical surgery for breast cancer is the key to promote clinical homogenization for diagnosis and treatment of breast cancer.

Key words: breast cancer, radical surgery, standardized diagnosis and treatment