中国实用外科杂志

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胆囊癌新辅助治疗与手术时机选择

龚    伟,熊逸晨,杨自逸,吴向嵩   

  1. 上海交通大学医学院附属新华医院普外科 上海市胆道疾病研究重点实验室 上海市胆道疾病研究中心 上海交通大学医学院胆道疾病研究所,上海200092
  • 出版日期:2023-11-01

  • Online:2023-11-01

摘要: 胆囊癌新辅助治疗旨在通过实现术前辅助治疗,提升治疗效果,提高病人生存率。相较于其他肿瘤治疗,目前胆囊癌新辅助治疗尚处于初步阶段,对于临界可切除和局部进展期胆囊癌的定义、新辅助治疗的适合对象、最佳推荐方案、手术时机的选择,都存在争议。胆囊癌新辅助治疗期间,多学科团队应建立个体化、精准化新辅助治疗模式,早期、动态、全面评估疗效,优化治疗策略,改善胆囊癌病人的生存结局。

关键词: 胆囊癌, 新辅助治疗, 手术时机

Abstract: The strategy and timing of surgery of neoadjuvant therapy in gallbladder cancer        GONG Wei, XIONG Yi-chen, YANG Zi-yi, et al. Department of General Surgery, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai 200092, China
Correspondong author:GONG Wei,E-mail:gongwei@xinhua
med.com.cn
Abstract    Currently, neoadjuvant therapy for gallbladder cancer is still in an early stage compared with its achievement in other types of tumors. It is still a controversial in terms of the definition of borderline resectable or locally advanced gallbladder cancer, the selection of the best recommended protocol for neoadjuvant therapy, and the choice of timing for surgery after neoadjuvant therapy. A multidisciplinary team approach should be recommended to establish individualized and precise neoadjuvant therapy modality to dynamically and comprehensively evaluate the efficacy of neoadjuvant therapy at an early stage, optimize treatment strategies, and improve the therapeutic effect of gallbladder cancer patients.

Key words: gallbladder cancer, neoadjuvant therapy, surgery timing