中国实用外科杂志

中国实用外科杂志 ›› 2022, Vol. 42 ›› Issue (09): 1062-1064.DOI: 10.19538/j.cjps.issn1005-2208.2022.09.25

• 文献综述 • 上一篇    下一篇

基于SEER数据库儿童及青少年甲状腺癌诊治研究进展

王志宏，桂志强，张    浩   

  1. 中国医科大学附属第一医院甲状腺外科，辽宁沈阳110001
  • 出版日期:2022-09-01 发布日期:2022-09-20

  • Online:2022-09-01 Published:2022-09-20

摘要： 儿童及青少年甲状腺癌少见，与成人相比具有淋巴结转移发生率高、远处转移发生率高、复发率高、病死率低的特点。美国国家癌症研究所监测、流行病学和最终结果（SEER）数据库作为北美最具代表性的大型数据库之一，详细记录了儿童及青少年甲状腺癌病人的临床病理学特征，并且由于具有充足的病例数量使研究更具可信度。未来应继续研究针对儿童青少年甲状腺癌的精准预后评估方法，继续利用好SEER数据库这一样本量大的优点，在现有的研究基础上进一步细化和深入，以使这一特殊人群能够获得精准的个体化治疗方案以及预后的评估。

关键词: 儿童, 青少年, 甲状腺癌, 监测、流行病学和结果数据库（SEER）, 研究进展

Abstract: Progress in diagnosis and treatment of thyroid cancer in children and adolescents based on SEER database                      WANG Zhi-hong, GUI Zhi-qiang，ZHANG Hao.Department of Thyroid Surgery, the First Hospital of China Medical University, Shenyang 110001, China 
Corresponding author: ZHANG Hao, E-mail: haozhang@cmu.edu.cn
Abstract    Compared with adults, thyroid cancer in children and adolescents is characterized by high lymph node metastasis rate, high distant metastasis rate, high recurrence rate and low mortality rate. The Surveillance, Epidemiology, and End Results(SEER) database of the National Cancer Institute is one of the most representative large databases in North America, in which the clinicopathological features of thyroid cancer in children and adolescents are recorded in detail. The SEER database makes the study more reliable because of the sufficient number of cases. In the future, we should continue to study the accurate prognostic evaluation methods for thyroid cancer in children and adolescents, continue to make good use of the advantage of the large sample size of the SEER database, and further refine and deepen it based on the existing research, so that this special population can obtain accurate individualized treatment and prognosis evaluation.

Key words: children, adolescents, thyroid carcincancer, SEER, research progress