中国实用外科杂志

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医源性胆管损伤修复时机选择

梁廷波,马    涛   

  1. 浙江大学医学院附属第二医院肝胆胰外科,浙江杭州310009
  • 出版日期:2018-09-01 发布日期:2018-09-07

  • Online:2018-09-01 Published:2018-09-07

摘要:

医源性胆管损伤(BDI)是腹腔镜胆囊切除术(LC)的较常见并发症。手术修复是治疗胆管横断性损伤等严重BDI的最佳选择,但修复的时机目前并无共识。LC术中发现的BDI应即时修复并无较大争议,但应由经验丰富的胆道外科医师主刀进行,若条件不足建议放置引流后转至较大的胆道外科中心治疗。LC术后发现的BDI占大多数,既往认为延迟修复较早期修复更有优势,因此时炎性反应已控制,修复成功率更高;然而近期也有部分研究认为早期修复并不增加手术风险和并发症发生率,且可缩短治疗时间,提高病人的生活质量。这些截然不同的研究结论可能与BDI的严重程度、局部炎性反应程度、纳入病人的基础情况等的差异有关。故BDI手术修复的时机不能一概而论,应根据病人的全身病情及局部状况制定个体化的治疗策略,争取在提高修复成功率的同时改善病人的生活质量,减少住院时间及医疗费用。

关键词: 腹腔镜胆囊切除术, 胆管损伤, 修复手术, 时机

Abstract:

Timing of surgical repair after iatrogenic bile duct injury          LIANG Ting-bo, MA Tao. Department of Hepatobiliary and Pancreatic Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
Corresponding author: LIANG Ting-bo,E-mail:liangtingbo@
zju.edu.cn
Abstract    Iatrogenic bile duct injury (BDI) is a relatively common complication of laparoscopic cholecystectomy (LC). Surgical repair is the best choice for severe BDI including transection of major bile ducts. However,the timing of repairing operation is still controversial.There is little debate that prompt repair should be done by experienced surgeons if BDI is discovered during LC.It’s also recommended that simple drainage of the abdomen and referral to an experienced tertiary care center if the conditions for an optimal treatment are not available.BDI discovered post-LC is more common.Delayed repair is traditionally preferred over early repair as the success rate of repair is higher when local inflammation and sepsis are controlled. However,recent data reveal that early repair may shorten length of hospital stay and decrease the medical cost,without increasing surgical risks and post-operative complications. The conflicting conclusions from different studies may be explained by the differentiation of indication for both treatment options,the severity of the injury and local inflammation response,and the general condition of the patient.In conclusion,the timing of surgical repair for BDI should be tailored according to the local and general conditions of the patient. An individualized approach is recommended to improve the success rate of repair and the quality of life,and to decrease the length of hospital stay and medical cost.

Key words: laparoscopic cholecystectomy, bile duct injury, surgical repair, timing