Abstract: Alveolar bone loss and bone insufficiency caused by inflammation，trauma，and tumors are important problems faced by oral clinical natural tooth preservation and implantation. Barrier membrane-based guided bone regeneration is currently the most commonly used strategy for the restoration of alveolar bone defects. However，the existing barrier membrane-related products generally have problems such as single structural design，insufficient function，and poor mechanical properties. Therefore，the construction of new oral barrier membranes based on material engineering strategies to promote alveolar bone regeneration has been widely studied in recent years. According to the strategy of enhancing the function of oral barrier membranes，this paper discusses the research status of traditional barrier membranes，component-modified barrier membranes，and structure-optimized barrier membranes，and finally looks forward to the future development of oral barrier membranes.

Key words: barrier membrane, guided bone regeneration, modified component, optimized structure

摘要： 炎症、外伤、肿瘤等导致的牙槽骨缺失和骨量不足，是口腔临床天然牙保留和种植所面临的重要问题。基于屏障膜的引导骨再生术是目前临床修复牙槽骨缺损常用的策略。然而，现有屏障膜相关产品普遍存在结构设计单一、功能不足、机械性能差等问题。因此，基于材料工程学策略构建新型口腔屏障膜促进牙槽骨再生，近年来得到广泛研究。文章根据增强口腔屏障膜功能的策略，分类讨论了传统屏障膜、组分改良屏障膜和结构优化屏障膜的研究现状，并展望口腔屏障膜的未来发展。

关键词: 屏障膜, 引导骨再生, 组分改良, 结构优化