中国实用口腔科杂志

中国实用口腔科杂志 ›› 2025, Vol. 18 ›› Issue (5): 570-577.DOI: 10.19538/j.kq.2025.05.011

• 论著 • 上一篇    下一篇

数字化导板联合骨片保留技术在颌骨囊肿摘除术中的应用效果研究

郭    杰1，艾力麦尔旦·艾尼瓦尔1，2，王    玲1，2   

  1. 1. 新疆医科大学第一附属医院（附属口腔医院）口腔外科门诊，新疆 乌鲁木齐 830000；2. 新疆维吾尔自治区口腔医学研究所，新疆 乌鲁木齐 830000
  • 出版日期:2025-09-30 发布日期:2025-09-30
  • 通讯作者: 王玲
  • 基金资助:
    新疆医科大学第一附属医院青年科研启航专项基金（2022YFY-QKQN-33）

  • Online:2025-09-30 Published:2025-09-30

摘要： 目的    研究数字化导板联合骨片保留技术在颌骨囊肿治疗中的临床效果。方法    选取2023年10月至2024年10月于新疆医科大学第一附属医院（附属口腔医院）口腔外科门诊需行颌骨囊肿摘除术的患者40例，随机分为研究组和对照组（每组各20例）。研究组在囊肿摘除术中采用数字化导板联合骨片保留技术，并充填浓缩生长因子（concentrated growth factors，CGF）；对照组采用常规囊肿摘除术再充填CGF。比较2组患者的手术时间，术前1 d和术后1、3 d的C-反应蛋白（C-reactive protein，CRP）和白细胞（white blood cell，WBC）含量，术后1、3、7 d的疼痛视觉模拟量表（visual analogue scale，VAS）评分，术后3、7、14 d的Landry创面愈合指数，术后肿胀程度、并发症及术后1年复发情况，术前及术后3、6、12个月的术区骨密度灰度值，术前及术后6、12个月的病变骨腔体积。结果    研究组手术时间为（31.40 ± 5.34）min，对照组手术时间为（29.40 ± 4.78）min，2组间比较差异无统计学意义（t = 1.247，P = 0.220）。2组患者术前的CRP和WBC含量、术区骨密度灰度值、病变骨腔体积比较，差异均无统计学意义（均P > 0.05）；研究组术后1 d的CRP含量，术后6、12个月的病变骨腔体积较对照组明显减少，术后3、6个月的术区骨密度灰度值较对照组明显增加，差异均有统计学意义（均P < 0.05）。研究组术后1、3 d的VAS评分较对照组明显减少，术后7、14 d的Landry创面愈合指数较对照组明显增加，差异均有统计学意义（均P < 0.05）。2组患者的术后肿胀程度、并发症及术后1年复发情况比较，差异均无统计学意义（均P > 0.05）。结论    数字化导板联合骨片保留技术在颌骨囊肿治疗中能够实现精准定位，减少手术创伤，减轻术后疼痛，并有助于术区的软硬组织愈合，值得在临床推广应用。

关键词: 数字化导板, 颌骨囊肿, 骨片保留技术, 浓缩生长因子, 骨缺损

Abstract: Objective    To study the clinical effect of digital guide plate combined with bone slice preservation technology in the treatment of jaw cysts. Methods    Totally forty patients who needed jaw cyst enucleation in the outpatient department of oral surgery of the First Affiliated Hospital of Xinjiang Medical University（Affiliated Stomatological Hospital）from October 2023 to October 2024 were randomly divided into the study group and the control group（20 cases in each group）. In the study group，digital guide plate combined with bone slice preservation technology was used during cyst enucleation，and concentrated growth factors（CGF）were filled；the control group was treated with conventional cyst enucleation and then CGF were filled. The operation time，the content of C-reactive protein（CRP）and white blood cell（WBC）at 1 d before operation and 1 d and 3 d after operation，the visual analogue scale（VAS）score of pain at 1 d，3 d and 7 d after operation，the Landry wound healing index at 3 d，7 d and 14 d after operation，the degree of postoperative swelling，complications and recurrence at 1 year after operation，the gray value of bone mineral density in the operation area before operation and at 3 months，6 months and 12 months after operation，and the volume of lesion bone cavity before operation and at 6 months and 12 months after operation were compared between the two groups. Results    The operation time was（31.40 ± 5.34）min in the study group and（29.40 ± 4.78）min in the control group，and there was no significant difference between the two groups（t = 1.247，P = 0.220）. There was no significant difference in the preoperative CRP and WBC content，gray value of bone mineral density in the operation area，or volume of lesion bone cavity between the two groups（all P > 0.05）；in the study group，the CRP content at 1 d after operation and the volume of the lesion bone cavity at 6 months and 12 months after operation were significantly reduced compared with the control group，and the gray value of bone mineral density at 3 months and 6 months after operation was significantly increased compared with the control group，with statistically significant differences（all P < 0.05）. Compared with the control group，the VAS score of the study group at 1 day and 3 days after operation was significantly reduced，and the Landry wound healing index at 7 days and 14 days after operation was significantly increased，with statistically significant differences（all P < 0.05）. There was no significant difference in the degree of postoperative swelling，complications or recurrence at 1 year after operation between the two groups（all P > 0.05）. Conclusion    Digital guide plate combined with bone slice preservation technology in the treatment of jaw cysts can achieve precise positioning，reduce surgical trauma，reduce postoperative pain，and help the soft and hard tissue healing in the operation area，which is worthy of clinical application.

Key words: digital guide plate, jaw cyst, bone slice preservation technology, concentrated growth factors, bone defect