关键词: 白色念珠菌, 基因型, 家族传播, 龋病

Abstract:

Dental caries and familial transmission of oral Candida albicans. WU Fei，GONG Yan-bing, ZHANG Zhong-lin, WANG Mei-hui，JIANG Yong，ZHENG Jian-ling. Vocational Technology College of Liaoning Univercity of Traditional Chinese Medicine, Shenyang 110101, China Abstract： Objective To explore the relationship between dental caries and the familial transmission of oral Candida albicans. Methods A total of 35 families (119 samples) dental plaque samples were collected. PCR ITS1-ITS2 method was preformed for identification of Candida albicans genotype. Analyze familial transmission and DMFT. Results A total of 34 samples(34／119，28.6%)in 18 families (18／35，51.4%) were found to be Candida albicans carriers, 11 families（11／18，61.1%） showed familial transmission. The similar rate of Candida albicans genotypes in family was 0（0／5）in vertical transmission（mother／father to baby），66.7%（2／3）in vertical-horizontal transmission，66.7%（2／3） in horizontal transmission. The difference was statistically significant in Candida albicans genetype morphology of family transmission （x2 = 26.571, P<0.01）. The correlation between Candida albicans infection and dental caries was not statistically significant. Conclusion Candida albicans genotype shows significant polymorphism in familial transmission. The correlation between Candida albicans infection and dental caries is not statistically significant.

Key words: Candida albicans, genotype, familial transmission, dental caries