关键词: 机械力, 牙周膜细胞, 破骨细胞, 牙根吸收

Abstract: Periodontal ligament cells（PDLCs）are common cells in periodontal tissues，and they play important roles in maintaining the morphological and functional integrity，force distribution，and homeostasis protection of periodontal tissues. PDLCs are a kind of mechano-sensory cells that can convert mechanical force signals into biological signals，which can regulate the biological behaviors of the downstream cells. Osteoclasts（OCs）are the main functional cells during root resorption，and their viability and quantity are regulated by PDLCs. This paper reviews the research progress on how PDLCs regulate OCs under various mechanical stimulation，and aims to provide new ideas and methods for the prevention and treatment of root resorption.

Key words: mechanical force, periodontal ligament cells, osteoclast, root resorption