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02 November 2022, Volume 38 Issue 11 Previous Issue   

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Fertility preservation in patients with vulvar and vaginal cancer. YAO Ting-ting, FU Zhao-jie, LIN Zhong-qiu 2022, 38(11): 1063-1067.  DOI: 10.19538/j.fk2022110102 Abstract ( )   Vulval and vaginal caner usually occurs in postmenopausal women. Fertility preservation is only applicable to a few young women，who are diagnosed during non-pregnancy，pregnancy or childbirth. According to the age，whether there is a need for fertility，the time of discovery，stage and pathological type，different treatment methods are selected.

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Treatment and long-term management of fertility-sparing in early-stage endometrial cancer.  PAN Ling-ya, CHEN Jia-yu 2022, 38(11): 1068-1074.  DOI: 10.19538/j.fk2022110103 Abstract ( )   Young patients，who have a strong desire to preserve fertility and are diagnosed with grade 1 endometrioid carcinoma without myometrium invasion，may receive fertility-sparing therapy.  Treatment regimens include weight management，high-dose progesterone，levonorgestrel intrauterine device，other antiestrogens（gonadotrophin releasing hormone agonist，GnRH-a or aromatase inhibitors，AIs），hysteroscopic resection，and metformin. Assisted reproductive technology can significantly increase the pregnancy rate without affecting survival. Radical surgery is needed after the completion of reproduction，and bilateral ovaries can be retained for young patients.

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Status of fertility preservation in ovarian cancer. XU Fei, WU Xiao-hua 2022, 38(11): 1074-1079.  DOI: 10.19538/j.fk2022110104 Abstract ( )   The age of women diagnosed with ovarian cancer is gradually getting younger，3% to 14% of patients are diagnosed at reproductive age，and the overall 5-year survival rate of women younger than 44 years old in stages IA to IB is as high as 91.2%. Therefore，the treatment that preserves the reproductive function of patients without affecting the survival rate is increasingly important. This article mainly describes the current status of fertility-sparing surgical treatment and assisted reproductive technology for ovarian malignant tumors.

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Research progress of fertility protection in gestational trophoblastic tumors. ZHAO Jun, XIANG Yang 2022, 38(11): 1079-1083.  DOI: 10.19538/j.fk2022110105 Abstract ( )   Gestational trophoblastic neoplasms（GTNs） include invasive hydatidiform mole，choriocarcinoma，placental site trophoblastic tumors and epithelioid trophoblastic tumors. GTN mostly occurs in women of child-bearing age，so it is particularly important to preserve the fertility of patients. This paper expounded the methods of fertility-sparing treatments for GTN，such as systemic intravenous chemotherapy or arterial intubation chemotherapy，arterial embolization，conservative surgery，and immunotherapy. The pregnancy outcomes after fertility-preserving treatment were summarized.

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Preservation of fertility in women with tubal diseases. GUAN Jing 2022, 38(11): 1083-1088.  DOI: 10.19538/j.fk2022110106 Abstract ( )   Tubal factor infertility accounts for about 30% to 35% of the infertility population. With the in-depth application of laparoscopic technique and the principle of minimally invasive surgery，micro-invasive surgical treatment for reproductive tubal diseases has attracted much attention. Surgical treatment for tubal infertility plays an important role in evaluating tubal function，preserving female fertility and improving the outcome of natural pregnancy or assisted reproduction. This article mainly describes the treatment and clinical outcome of laparoscopic surgery to preserve and recover fertility in patients with tubal disease.

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Thoughts on clinical strategy for fertility protection in endometriosis. SUN Jin-li, CHEN Qiong-hua 2022, 38(11): 1088-1092.  DOI: 10.19538/j.fk2022110107 Abstract ( )   Endometriosis （EM for short） is a common disease that leads to the decline of female fertility. The way to fulfill the concept of fertility protection throughout the whole process，and the use of this as a starting point to formulate appropriate individualized comprehensive treatment strategies for patients with endometriosis so as to maximize the treatment outcome has always been the difficulty and the focus of endometriosis treatment. This paper summarizes and analyzes the treatment dilemma of endometriosis and the change of treatment mode，considers the core value of endometriosis treatment，and analyzes the optimal strategies at different stages. It is proposed that the treatment for endometriosis should be age-stratified，symptom-oriented，and coupled with three-level prevention，taking the improvement of patients' quality of life as the core，so that a precise whole-process management mode of chronic diseases can be carried out.

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Perioperative treatment for intrauterine adhesion based on female fertility protection.  PAN Ning-ning, LI Rong 2022, 38(11): 1092-1096.  DOI: 10.19538/j.fk2022110108 Abstract ( )   Intrauterine adhesion is a disease secondary to endometrial injury，which seriously affects female fertility. This article systematically reviews the etiology，pathogenesis，clinical manifestations，diagnosis and treatment of intrauterine adhesions，focusing on the perioperative treatment strategies for intrauterine adhesion based on female fertility protection.

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Research progress in new technology of ovarian fertility preservation in oncofertility. HUANG Zhi-xiong, YAN Xiao-hong, XIAO Shuo 2022, 38(11): 1096-1100.  DOI: 10.19538/j.fk2022110109 Abstract ( )   Oncofertility，dedicates to preserving the fertility and related reproductive endocrine functions of cancer patients. Ovarian function is essential to maintaining fertility and endocrine function in young female cancer survivors. This paper aims to summarize the current research in new technologies for ovarian fertility preservation，in order to provide reference for the theoretical research and clinical practice of ovarian fertility preservation in cancer patients.

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中国抗癌协会妇科肿瘤专业委员会 2022, 38(11): 1108-1110.  DOI: 10.19538/j.fk2022110111 Abstract ( )