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02 February 2021, Volume 37 Issue 2 Previous Issue    Next Issue

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Risk and prevention of long-term cardiovascular diseases and other diseases in preeclampsia. XU Huang-fang，LI Xiao-tian 2021, 37(2): 142-145.  DOI: 10.19538/j.fk2021020103 Abstract ( )   Preeclampsia refers to a common obstetric disease with elevated blood pressure and proteinuria as the main symptoms after 20 weeks of gestation，which is one of the main reasons leading to the rise in maternal morbidity and mortality worldwide. There is growing evidence that the maternal effects of preeclampsia are not limited to pregnancy and puerperium. Women with preeclampsia are at increased risk of developing cardiovascular disease，kidney disease，metabolic syndrome，thromboembolism and diabetes in the future. Strengthening assessment of risk factors，early intervention and clinical monitoring will help reduce the risk of long-term adverse prognosis for women with preeclampsia，which is of great significance for the prevention and treatment of preeclampsia-related cardiovascular diseases，kidney diseases and so on.

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Recurrent preeclampsia. HE Ying-dong，CHEN Qian 2021, 37(2): 145-149.  DOI: 10.19538/j.fk2021020104 Abstract ( )   Preeclampsia is a severe complication during pregnancy.With the adjustment of national fertility policy，recurrent preeclampsia is a new clinical problem for Obstetrics. In this paper，we will introduce the incidence，risk factors，prevention of recurrent preeclampsia and prenatal care of patients with history of preeclampsia，in order to improve the prognosis of these patients.

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Long-term effect of uterine preserving treatment for placenta accreta. ZHAO Xian-lan，TAO Ya 2021, 37(2): 149-152.  DOI: 10.19538/j.fk2021020105 Abstract ( )   Placenta accreta，as an obstetrical conundrum，often leads to perinatal hemorrhage，which is difficult to control and endangers the life of pregnant women. The incidence and diagnosis rate of placenta accreta is increasing year by year and more and more women are being diagnosed due to the high rate of cesarean section，the adoption of a domestic second-child policy and the development of imaging technology. To date，worldwide guidelines or consensuses still consider hysterectomy as a mainstay in the treatment of placenta accreta. With the development of obstetric hemostasis and interventional surgery，and with the increase of patient's willingness to retain the uterus，conservative surgical treatments for placenta accreta have gained increasing popularity and acceptance all over the world and have shown more and more advantages. Of these，the "3- Procedure" surgery has been widely adopted，modified and promoted，and based on the conditions of hospital equipment and the experience of obstetricians，different methods have been used to block the uterine blood vessels， followed by partial placental-myometrium resection and uterine reconstruction. In this way， blood loss can be greatly reduced while the uterus could be， most likely，preserved， thereby avoiding hysterectomy and related adverse effects.

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Effects of gestational diabetes mellitus on the incidence of long- term diabetes of female. CUI Jian-jian，LI Zhu-yu 2021, 37(2): 152-156.  DOI: 10.19538/j.fk2021020106 Abstract ( )   Gestational diabetes mellitus（GDM）is a common complication of pregnancy. Poor control of blood glucose can lead to serious adverse outcomes of pregnancy，and threaten the health of mothers and children. Although most GDM patients can have normal glucose metabolism level after delivery， the patients with a history of GDM have an increased risk of abnormal glucose metabolism during second pregnancy，and with the survival time prolonged，the risk of obesity，diabetes and cardiovascular disease will increase significantly. Strengthening the research of postpartum glucose metabolism in patients with GDM can contribute to reducing the risk of long-term diabetes.

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Effect of hysterectomy on life quality after postpartum hemorrhage. ZHANG Xue-mei，QI Hong-bo 2021, 37(2): 156-159.  DOI: 10.19538/j.fk2021020107 Abstract ( )   Postpartum hemorrhage remains the leading cause of maternal death globally. Early identification and early treatment to avoid a series of complications caused by severe bleeding is extremely important. When bleeding cannot be controlled and endangers the life of the mother，timely hysterectomy is the most effective treatment. The sexual life and mental health status of patients will be affected after hysterectomy.

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Influence of vaginal delivery and cesarean section on pelvic floor function in women. LIU Juan，LIU Qi-huang 2021, 37(2): 159-162.  DOI: 10.19538/j.fk2021020108 Abstract ( )   Pelvic Floor Dysfunction（PFD）is a disease with symptoms of pelvic organ prolapse（POP），urinary incontinence（UI），and fecal incontinence（FI）. Pregnancy and delivery are the main factors for the occurrence of postpartum PFD. Previous studies have shown that the occurrence of PFD after delivery is related to vaginal delivery，while cesarean section can prevent the occurrence of PFD. However，the risk of the occurrence of PFD due to vaginal delivery and cesarean section remains controversial.The paper discussed the effects of different delivery modes on pelvic organ prolapse，urinary incontinence and fecal incontinence，and explored the correlation between delivery mode and PFD.

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Long-term effects of fetal growth restriction on offspring. SHENG Chao，WANG Zhi-jian 2021, 37(2): 162-165.  DOI: 10.19538/j.fk2021020109 Abstract ( )   Fetal growth restriction （FGR） is one of the major factors leading to perinatal disease and death. FGR has long-term adverse effects on offspring，increasing the risk of chronic non-infectious diseases  adult，such as neurodevelopmental disability，diabetes，coronary heart disease and hypertension. Based on the relevant clinical studies，this review summarizes the long-term effects of FGR on offspring.

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Influence of intrauterine microenviroment on long-term health complications in offspring. DENG Na，WANG Hai-bin 2021, 37(2): 165-169.  DOI: 10.19538/j.fk2021020110 Abstract ( )   Intrauterine homeostasis during pregnancy is essential for optimal fetal growth and development. In face of poor intrauterine microenviroment，the fetus may have some adaptive changes through fetal programming in order to survive，which may lead to increased risk of chronic non-infectious diseases in later life. There has been evidence that epigenetics plays a significant role in fetal programming. This article focuses on the relationship between fetal programming and epigenetic changes as well as potential epigenetic regulator，which is aimed to identify biomarkers for predicting infants at high risk of adult-onset diseases and to provide new directions for early intervention and treatment of long-term complications in offspring.

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Long-term effects of the use of antenatal corticosteroid on the mental system of the offspring. LIU Yan-yan，FENG Ling 2021, 37(2): 169-171.  DOI: 10.19538/j.fk2021020111 Abstract ( )   The use of antenatal corticosteroid is an important prenatal intervention to promote fetal lung maturity and improve the prognosis of preterm infants. It is an independent protective factor for the survival of preterm infants. At the same time，attention should be paid to its potential long-term effects on the nervous system of the offspring.