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02 January 2021, Volume 37 Issue 1 Previous Issue    Next Issue

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Standardized diagnosis of cervical cancer. KANG Shan 2021, 37(1): 37-41.  DOI: 10.19538/j.fk2021010109 Abstract ( )   The standardized diagnosis of cervical cancer is a prerequisite for standardized treatment of cervical cancer. The etiology of cervical cancer is clear，and its occurrence and development is a gradual process with its distinctive characteristics. It usually takes 8 to 10 years from continuous HPV infection to intraepithelial neoplasia，and then to invasive cancer. The focus of diagnosis at this stage is to screen through HPV detection，and sometimes assisted cytopathological examination is needed. The stage of invasive cancer progresses rapidly，and the diagnosis mainly depends on histopathological biopsy and radiographic examination，such as colposcopy，histological bite examination，endocervical canal curettage，conization，CT or MRI. The main purpose of pre-screening is to find treatable precancerous lesions that can develop into invasive cancer so as to reduce the morbidity，mortality and treatment-related complications of cervical cancer，and another purpose is to find early invasive cancer. All the methods adopted in the later stage of invasive cancer are to make a clear diagnosis and staging in order to make reasonable and accurate treatment decisions.

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Standardized evaluation of cervical cancer patients before treatment. LIU Ping，LI Peng-fei 2021, 37(1): 41-44.  DOI: 10.19538/j.fk2021010110 Abstract ( )   In the International Federation of Gynecology and Obstetrics 2018 staging system of cervical cancer，pathological results and imaging findings can be used to correct the clinical staging，but the clinical staging and treatment methods for untreated patients mainly depend on clinical evaluation. So standardized clinical evaluation is the premise and basis of standardized treatment.In terms of the problems in clinical evaluation of newly diagnosed cervical cancer patients，we put forward standardized clinical evaluation suggestions and strategies，in which new technologies and methods are involved.

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Standardization of preoperative adjuvant therapy for cervical cancer. HE Gui-fang，LING Bin 2021, 37(1): 44-48.  DOI: 10.19538/j.fk2021010111 Abstract ( )   Neoadjuvant chemotherapy（NACT）is the primary preoperative adjuvant therapy for cervical cancer. In principle，it is suitable for patients with locally advanced cervical cancer（ⅠB3-ⅣA）and some special types of cervical cancer. Cisplatin is the preferred drug，and chemotherapy for 2-3 courses is recommended. Some patients with stage ⅠB3-ⅡA2 cervical squamous cell carcinoma and adenocarcinoma with tumor diameter larger than 4 cm can be treated with radical surgery and pelvic lymphadenectomy after neoadjuvant chemotherapy. For small cell neuroendocrine tumors of the cervix，hysterectomy is performed after neoadjuvant chemotherapy，and then postoperative adjuvant radiotherapy or concurrent chemoradiotherapy is performed，followed by other systemic treatments. It is very important to standardize the application of NACT in preoperative adjuvant treatment of cervical cancer，strictly grasp the indications and contraindications，and give full play to its therapeutic advantages.

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Standardization of C1 radical hysterectomy for cervical cancer. LU An-wei，ZHOU Li 2021, 37(1): 48-51.  DOI: 10.19538/j.fk2021010112 Abstract ( )   Extensive hysterectomy combined with pelvic lymphadenectomy is a common operation for early invasive cervical carcinoma，and postoperative urinary retention is the most common complication. C1 radical hysterectomy for cervical cancer is an important part of Q-M classification. The rate of urinary dysfunction after C1 radical hysterectomy could be significantly reduced. This paper discusses the controversy of C1 radical hysterectomy，the  related anatomical structures and the key steps of C1 radical hysterectomy.

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Standardization of postoperative adjuvant treatment for cervical cancer. HUANG He，LIU Ji-hong 2021, 37(1): 51-54.  DOI: 10.19538/j.fk2021010113 Abstract ( )   Postoperative adjuvant therapy is an important part of the treatment for early-stage cervical cancer. According to the classification of postoperative pathological factors，we discuss the standardized adjuvant therapy recommended by the current guidelines and the progress in this field. We aim to explore the reasonable adjuvant treatment made for early-stage cervical cancer after surgery.

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Standardized radiotherapy for cervical cancer. WU De-hua 2021, 37(1): 54-59.  DOI: 10.19538/j.fk2021010114 Abstract ( )   Cervical cancer is one major disease affecting the health of Chinese women. With the deepening understanding of the disease，a comprehensive treatment model that combines surgery，radiotherapy and chemotherapy has become increasingly mature. Based on different stages of cervical cancer，this article systematically expounds the application and value of radiotherapy in the treatment of cervical cancer，in order to provide reference for clinical decision-making.

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Standardization of clinical research related to cervical cancer. QU Qing-xi，ZHANG Shi-qian 2021, 37(1): 59-63.  DOI: 10.19538/j.fk2021010115 Abstract ( )   In this report，we reviewed the current situation and problems of clinical diagnosis and treatment of cervical cancer. We proposed that clinical research is the driving force to lead the development of medicine through the example of LACC research and KEYNOTE-158 study.We then analyzed the tortuous process of standardization of clinical research in China. In last，we discussed the prospect that gynecological oncologists advocated original，standard clinical research of cervical cancer in line with national conditions in China.

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Prevention and treatment of complications of radical hysterectomy. LIU Kai-jiang 2021, 37(1): 63-66.  DOI: 10.19538/j.fk2021010116 Abstract ( )   Classic radical hysterectomy is an anatomical and normative surgery，but it is also a high risk surgery with various complications and calls for skilled performance. Therefore，it is necessary to standardize surgical operation，which helps to avoid the occurrence of vascular，nerve and organs damage during surgery.