ZHANG Zhan-xin,LOU Xue-ling,YAO Li.. The role of SREBP1 in the oncogenesis and development of cervical cancer.[J]. Acta Metallurgica Sinica, DOI: 10.7504/fk2015060121.
[1] Jemal A,Bray F,Center MM,et al. Global cancer statistics[J]. CA,2011,61:69-90. [2] Fang J,Zhang H,Jin S. Epigenetics and cervical cancer:from pathogenesis to therapy[J]. Tumour Biol,2014, 35(6):5083-5093.[3] Deberardinis RJ,Sayed N,Ditsworth D,et al. Brick by brick:metabolism and tumor cell growth[J]. Curr Opin Genet Develop,2008,18(1):54-61. [4] Swinnen JV,Brusselmans K,Verhoeven G. Increased lipogenesis in cancer cells:new players,novel targets[J]. Curr Opin Clin Nutr Metab Care,2006,9(4):358-365. [5] Menendez JA,Lupu R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis[J]. Nat Rev Cancer,2007,7(10):763-777. [6] Ren S,Li X,Rodriguez-Agudo D,et al. Sulfated oxysterol,25HC3S,is a potent regulator of lipid metabolism in human hepatocytes[J]. Biochem Biophys Res Commun,2007,360(4):802-808. [7] Li W,Tai Y,Zhou J,et al. Repression of endometrial tumor growth by targeting SREBPl and lipogenesis[J]. Cell Cycle 2012,11(12):2348-2358. [8] Yamashita T,Honda M,Takatori H,et al. Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma[J]. J Hepatol,2009,50(1):100-110. [9] Fimita E,Pai SK,Zhan R,et al. Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1[J]. Cancer Res,2008,68(4):1003-1011. [10] Migita T,Ruiz S,Fornari A,et al. Fatty acid synthase:a metabolic enzyme and candidate oncogene in prostate cancer[J]. J Natl Cancer Inst,2009,101(7):519-532. [11] Jung SY,Jeon HK,Choi JS,et al. Reduced expression of FASN through SREBP-1 down-regulation is responsible for hypoxic cell death in HepG2 cell[J]. J Cell Biochem,2012,113(12):3730-3739.[12] Vazquez-Martin A,Colomer R,Brunet J,et al. Overexpression of fatty acid synthase gene activates HERl /HER2 tyrosine kinase receptors in human breast epithelial cells[J]. Cell Prolif,2008,41(1):59-85.[13] Menendez JA,Lupu R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis[J]. Nat Rev Cancer,2007,7(10):763-777.[14] Lupu R,Menendez JA. Targeting fatty acid synthase in breast and endometrial cancer:an alternative to selective estrogen receptor modulators?[J]. Endocrinology,2006,147(9):4056-4066. [15] Eberhard Y,Gronda M,Hurren R,et al. Inhibition of SREBP1 sensitizes cells to death ligands[J]. Oncotarget,2011,2(3):186-196. [16] Yamashita T,Honda M,Takatori H,et al. Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma[J]. J Hepatol,2009,50(1):100-110. [17] Li JN,Mahmoud MA,Han WF,et al. Sterol regulatory element-binding protein-1 participates in the regulation of fatty acid synthase expression in colorectal neoplasia[J]. Experim Cell Res,2000,261(1):159-165. [18] Rahaman MT,Nakayama K,Ishikawa M,et al. Fatty acid synthase is a potential therapeutic target in estrogen receptor-/progesterone receptor-positive endometrioid endometrial cancer[J]. Oncology,2013,84(3):166-173.[19] DeAngelis T,Wu K,Pestell R,et al. The type 1 insulin-like growth factor receptor and resistance to DACH1[J].Cell Cycle,2011,10(12):1956-1959.[20] Lee MY,Moon JS,Park SW,et al. KLF5 enhances SREBP-1 action in androgen-dependent induction of fatty acid synthase in prostate cancer cells[J].Biochem J,2009,417(1):313-322.(2015-02-04收稿 2015-04-05修回)