Acta Metallurgica Sinica

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The value of tumor markers in prediction of ovarian cancer prognosis.

CAI Jing, WANG Ze-hua.   

  1. Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430022,China
  • Online:2015-03-02 Published:2015-04-01

肿瘤标志物预测卵巢癌预后的价值

蔡晶王泽华   

  1. 作者单位:华中科技大学同济医学院附属协和医院妇产科,湖北 武汉 430022
  • 通讯作者: 王泽华

Abstract:

Abstract:A precise prediction of tumor prognosis is essential to promoting the individualized therapy for ovarian cancer. Both protein and non-coding RNA are potential predictive factors, and a series of tumor markers have been proved to be significantly associated with overall survival, progression-free survival and/or response to chemotherapy in patients with ovarian cancer. However, further validations are required before any of the biomarkers can be applied to clinical prediction.

Key words: ovarian cancer, tumor marker, prognosis, survival, response to chemotherapy

摘要:

对卵巢癌预后进行准确预测是个体化治疗的基础和推动力。无论蛋白还是非编码RNA,都有作为卵巢癌预后预测因子的潜能。已经研究证实其中的一些肿瘤标志物与卵巢癌的总生存、无进展生存和(或)化疗反应性密切相关,但在用于临床之前还需要进一步验证。

关键词: 卵巢癌, 肿瘤标志物, 预后, 生存, 化疗反应性

CLC Number: