The complications of ovulation induction and its prevention.

doi:10.7504/fk2014120109

Abstract

Abstract:

Abstract: Induction of ovulation often results in multiple follicular development and complications increase signi?cantly, such as multiple pregnancy, ovarian hyperstimulation syndrome (OHSS), ectopic pregnancy, and ovarian tortion. These complications are rare, but can be severe and even life-threatening. It is obvious that the best strategy is prevention of the occurrence rather than dealing with the problem after its occurrence.

Key words: induction of ovulation, complication, ovarian hyperstimulation syndrome, multiple pregnancy

摘要：

临床上促排卵治疗常常致多个卵泡发育，在提高妊娠率的同时也带来诸多并发症，如多胎妊娠、卵巢过度刺激综合征（OHSS）、异位妊娠和卵巢扭转等。虽然这些并发症并不多见，但有时会非常严重，甚至威胁生命。因此，促排卵过程中应加强监测，防范重于治疗。

关键词: 促排卵, 并发症, 卵巢过度刺激综合征, 多胎妊娠

CLC Number:

R321-33

MA Cai-hong,WANG Yang.. The complications of ovulation induction and its prevention.[J]. Acta Metallurgica Sinica, DOI: 10.7504/fk2014120109.

马彩虹，王洋. 促排卵并发症及其防治[J]. 中国实用妇科与产科杂志, DOI: 10.7504/fk2014120109.

References

［1］   Mathur RS, Akande AV, Keay SD,et al.Distinction between early and late ovarian hyperstimulation syndrome［J］.Fertil Steril,2000,73(5):901-907.

［2］    范燕宏，陈贵安，王海燕. 血管紧张素Ⅱ及其受体在人卵巢的表达［J］.生殖医学杂志，2004,13(3):146-149.

［3］   Golan A, Ronel R, Herman A,et al.Ovarian hyperstimulation syndrome: an update review［J］. Obstet Gynecol Surv，1989，44(6):430-440.

［4］   Humaidan P, Quartarolo J,Papanikolaou EG.Preventing ovarian hyperstimulation syndrome:guidance for the clinician［J］.Fertil Steril, 2010,94(2):389-400.

［5］   Humaidan P, Quartarolo J,Papanikolaou EG.Preventing ovarian hyperstimulation syndrome:guidance for the clinician［J］.Fertil Steril, 2010,94(2):389-400.

［6］   Cha KY, Koo JJ,Choi DH,et al. Pregnancy after in vitro fertilization of human follicular oocytes collected from nonstimulated cycles, their culture in vitro and their transfer in a donor oocyte program［J］. Fertil Steril,1991,55(1):109-113.

［7］   Youssef MA, van Vely M, Hassan MA, et al. Can dopamine agonists reduce the incidence and severity of OHSS in IVF/ICSI treatment cycles? A systematic review and meta-analysis［J］. Hum Reprod Update,2010, 16:459-466.

［8］   Tang H, Hunter T, Hu Y, et al. Cabergoline for preventing ovarian hyperstimulation syndrome［J］. Cochrane Database Syst Rev, 2012, 2:CD0086005.

［9］    Schade R, Andersohn F, Suissa S, et al. Dopamine agonists and the risk of cardiac-valve regurgitation［J］. N Engl J Med, 2007,356:29-38.

［10］    Izgi C, Feray H, Cevik C, et al. Severe tricuspid regurgitation in a patient receiving low-dose cabergoline for the treatment of acromegaly［J］. J Heart Valve Dis, 2010,19:797-800.

［11］   Sherwal V, Malik S, Bhatia V. Effect of bromocriptine on the severity of ovarian hyperstimulation syndrome and outcome in high responders undergoing assisted reproduction［J］. J Hum Reprod Sci,2010,3:85-90.

［12］   Soares SR. Etiology of OHSS and the use of dopamine agonists［J］. Fertil Steril,2012,97:517-522.

［13］   Schieve LA，Meikle SF，Feree C，et al．Low and very low birth weight in infants conceived with use of assisted reproductive technology［J］．N Engl J Med, 2002,346(10)：731-736.

［14］   Simmons R，Doyle P， Maconochie N．Dramatic reduction in tfplet and higher order biahs in England and Wales［J］．Br J Obstet Gynaeeol，2004，111(8)：856-858．

［15］    Kerenyi TD, Chitkara U. Selective birth in twin pregnancy with discordancy for Down’s syndrome［J］.N Engl J Med,1981,304:1525-1527.

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