Abstract: Ovarian cancer is the leading cause of gynecologic cancer death in the world，and there is clear evidence that some ovarian cancers have a high genetic risk. It is recommended to radicalize management，using risk-reducing bilateral salpingo-oophorectomy in hereditary ovarian cancer. This topic will discuss some topics related to risk-reducing bilateral salpingo-oophorectomy in hereditary ovarian cancer population.

Key words: ovarian cancer, risk-reducing, bilateral salpingo-oophorectomy, hereditary ovarian cancer

摘要： 卵巢癌病死率居女性生殖系统恶性肿瘤首位，目前有明确证据证实一部分卵巢癌具有遗传高风险。预防性附件切除术是降低遗传性卵巢癌发病风险的一级预防方案，但临床实践中应充分权衡利弊，科学规范应用。文章主要阐述了预防性附件切除术在降低遗传性卵巢癌发病风险中的作用及其应用指征、技术细节和相关争议问题。

关键词: 卵巢癌, 降低风险, 预防性附件切除术, 遗传性卵巢癌