关键词: 子宫颈癌, 新辅助化疗, 敏感性, 预测

Abstract: Cervical cancer is one of the common malignant tumors in women，which seriously threatens women's life and health. At present，neoadjuvant chemotherapy（NACT）is an important adjuvant treatment for cervical cancer before surgery or radiotherapy in China. However，due to the tumor heterogeneity of cervical cancer and individual differences in patients' sensitivity to chemotherapy，not all patients can benefit from NACT treatment. A simple and effective means to predict patients' chemotherapy sensitivity to NACT in a timely manner would help clinicians to adjust treatment plans in a timely manner and prevent patients who are not sensitive to NACT from missing the best opportunities for surgery or radiotherapy. This article presents the research progress on the prediction of NACT sensitivity in cervical cancer in terms of histopathology，biomarkers of patients and models of cancerous organs from patients，which will help to identify whether patients will benefit from NACT，stratify patients with different sensitivities，and promote the precise treatment of cervical cancer.

Key words: cervical cancer, neoadjuvant chemotherapy, sensitivity, prediction