关键词: 妊娠间隔, 母体结局, 胎儿结局, 早产, 子痫前期

Abstract: Both short（≤6-18 months）and long（＞60 months）interpregnancy interval（IPI）correlates with adverse maternal and fetal outcomes.In fetal outcome，short IPI increases the incidence of preterm birth，low birth weight and small for gestational age.In maternal outcome，long IPI increases the incidence of preeclampsia，short IPI increases the incidence of uterine rupture during trial of labor after previous cesarean section.Considering IPI is a potentially modifiable factor.It is recommended to advise the optimal interpregnancy interval in pregnant women individually after delivery in order to improve next pregnancy outcome.

Key words: interpregnancy interval, maternal outcome, fetal outcome, preterm birth, preeclampsia