中国实用妇科与产科杂志

中国实用妇科与产科杂志 ›› 2023, Vol. 39 ›› Issue (2): 139-143.DOI: 10.19538/j.fk2023020105

• 专题笔谈 • 上一篇    下一篇

阴道用孕酮预防子宫颈缩短导致的早产

  

  1. 中国医科大学附属盛京医院妇产科 国家卫生健康委员会生殖健康与遗传医学重点实验室 辽宁省母胎医学重点实验室 中国医科大学出生队列研究中心，辽宁 沈阳 110004
  • 出版日期:2023-02-02 发布日期:2023-03-02
  • 通讯作者: 乔宠
  • 基金资助:
    国家重点研发计划（2016YFC1000404）；国家自然科学基金面上项目（81370735，81771610）；沈阳市科技计划项目（20-205-4-004）；百千万人才工程领军人才（XLYC2005008）；辽宁省民生科技计划联合计划项目（2021JH2/10300123）；盛京自由研究者基金（201706）；辽宁省特聘教授（2017）

Research progress in the prevention of preterm birth caused by cervical shortening with vaginal progesterone.

  1. Department of Obstetrics and Gynecology，Key Laboratory of Reproductive and Genetic Medicine，National Health Commission，Key Laboratory of Maternal-Fetal Medicine of Liaoning Province，Research Center of China Medical University Birth Cohort，Shengjing Hospital of China Medical University，Shenyang 110004，China
  • Online:2023-02-02 Published:2023-03-02

摘要： 子宫颈缩短是指妊娠中期经阴道超声测量的子宫颈长度≤25mm，对于预测自发性早产和指导先兆早产临床决策具有重要意义。近些年，国内外学者开始关注子宫颈缩短的高危因素、筛查方案及治疗手段。文章从妊娠期子宫颈缩短的高危因素谈起，阐述孕酮尤其是阴道用孕酮治疗子宫颈缩短的机制、适应证及临床疗效，为防治早产提供参考依据。

关键词: 阴道用孕酮, 子宫颈, 早产

Abstract: Cervical shortening means that the length of cervix is less than 25mm measured by vaginal ultrasound in the second trimester，which is of great significance for predicting spontaneous preterm birth and guiding clinical decision-making of threatened preterm birth.In recent years，many scholars start paying attention to high-risk factors，methods and the treatment strategies of cervical shortening.The review summarized the high-risk factors and mechanisms，indications，and clinical effects of progesterone，especially vaginal progesterone，in treating cervical shortening，in order to provide reference for the prevention and treatment of preterm birth.

Key words: vaginal progesterone, cervix, preterm birth

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