中国实用妇科与产科杂志
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摘要： 早发性卵巢功能不全（POI）指女性在40岁之前卵巢活动衰退的临床综合征，以月经紊乱伴高促性腺激素及低雌激素为特征。POI患者可出现潮热、出汗等绝经期症状，远期可发生骨质疏松、心血管疾病等问题。激素补充治疗（HRT）是POI患者的有效治疗方法。文章对POI患者应用HRT的获益及可能存在的风险进行综合分析与评价。
关键词: 早发性卵巢功能不全, 激素补充治疗, 利弊
Abstract: Premature ovarian insufficiency（POI）is a clinical syndrome of decreased ovarian activity in women before the age of 40 years old，characterized by menstrual disorders with high gonadotropin and low estrogen.The women with POI may have hot flashes，night sweats and other menopausal symptoms，and they may have osteoporosis，cardiovascular diseases and other problems in the long term.Hormone replacement therapy（HRT）is an effective treatment for patients with POI.We will analyze and evaluate the benefits and possible potential risks of HRT in women with POI.
Key words: premature ovarian insufficiency, hormone replacement therapy, benefits and risks
中图分类号:
R711.75
曹金翔，吴洁. 早发性卵巢功能不全激素补充治疗利弊评价[J]. 中国实用妇科与产科杂志, DOI: 10.19538/j.fk2020030111.
CAO Jin-xiang，WU Jie. Evaluation of benefits and risks of hormone replacement therapy for the women with premature ovarian insufficiency.[J]. Acta Metallurgica Sinica, DOI: 10.19538/j.fk2020030111.
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https://www.zgsyz.com/zgsyfck/CN/Y2020/V36/I3/227
