中国实用妇科与产科杂志

中国实用妇科与产科杂志

• 专题笔谈 • 上一篇    下一篇

局部晚期宫颈癌放射治疗

  

  1. 重庆市肿瘤医院  重庆市肿瘤研究所 重庆大学附属肿瘤医院妇瘤中心，重庆 400030
  • 出版日期:2018-11-02 发布日期:2018-11-06
  • 通讯作者: 周琦
  • 基金资助:

    重庆市科学技术委员会重点基金项目（stc2015jcsf0007）

Radiotherapy for locally advanced cervical cancer.

  1. Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment，Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital，Chongqing 400030，China
  • Online:2018-11-02 Published:2018-11-06

摘要：

宫颈癌在发展中国家发病率仍较高，其中接近80%患者诊断为局部晚期宫颈癌（LACC）。美国国立综合癌症网络（NCCN）Ⅰ类推荐LACC患者治疗为盆腔放射治疗+腔内后装治疗+顺铂为基础同步化疗，目前LACC患者5年生存率仍徘徊在70%左右。文章结合相关文献，简述LACC患者放射治疗基本方法、原则及疗效，同时就提高放疗效果措施及进展，包括精准放疗、同步化疗、新辅助化疗、放疗后巩固化疗、手术病理分期及联合靶向治疗相关临床应用及研究展开综述及讨论。

关键词: 宫颈肿瘤, 局部晚期, 放疗, 化疗

Abstract:

The incidence of cervical cancer is still high in developing countries.Nearly 80% are diagnosed as locally advanced cervical cancer（LACC）.The National Comprehensive Cancer Network（NCCN）recommends that LACC patients be treated with pelvic radiotherapy，intracavitary brachytherapy and cisplatin-based concurrent chemotherapy.At present，the 5-year survival rate of LACC patients is still around 70%.In this paper，the basic methods，principles and therapeutic effects of radiotherapy for LACC patients are briefly reviewed，and the progress of radiotherapy，including precise radiotherapy，concurrent chemotherapy，neoadjuvant chemotherapy，post-radiotherapy consolidated chemotherapy，surgical pathological staging and combined targeted therapy，is reviewed and discussed.

Key words: cervical neoplasm, locally advanced, radiotherapy, chemotherapy

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