关键词: 宫颈肿瘤, 局部晚期, 新辅助化疗, 术前辅助放疗, 外照射放疗, 同步放化疗, 近距离放疗

Abstract:

The morbidity and mortality of cervical cancer in developing countries have been increasing year by year.Gynecologic oncologists face with huge challenges due to difficulty in treatment and poor prognosis of locally advanced cervical cancer.Owing to individual differences and uneven development of regional health services，the choices of treatment options for locally advanced cervical cancer remain controversial.Concurrent chemoradiotherapy is the standard treatment option for locally advanced cervical cancer in developed countries such as the United States and Canada.In Europe and Asia，especially in developing countries and regions，surgical treatment is selected after adjuvant therapy.This article describes the selection of preoperative treatments for locally advanced cervical cancer based on relevant literature and guidelines.

Key words: cervical neoplasm, locally advanced, neoadjuvant chemotherapy, preoperative radiotherapy, external-beam radiation therapy, concurrent chemoradiotherapy, brachytherapy