中国实用妇科与产科杂志

中国实用妇科与产科杂志

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上皮样滋养细胞肿瘤的诊治

  

  1. 浙江大学医学院附属妇产科医院，浙江 杭州 310006
  • 出版日期:2017-04-02 发布日期:2017-03-27
  • 通讯作者: 吕卫国

Diagnosis and treatment of epithelioid trophoblastic tumor

  1. Women’s Hospital School of Medicine，Zhejiang University，Hangzhou 310006，China
  • Online:2017-04-02 Published:2017-03-27

摘要：

上皮样滋养细胞肿瘤（epithelioid trophoblastic tumor，ETT）起源于绒毛膜型中间型滋养细胞，非常罕见，生育期年龄妇女多见，常继发于足月妊娠，临床表现与胎盘部位滋养细胞肿瘤（placental site trophoblastic tumor，PSTT）相似，约70％出现阴道流血，血hCG水平中度升高。手术是ETT主要的治疗手段，化疗效果目前仍存在争议。无转移者预后良好，但一旦转移预后极差。

关键词: 妊娠滋养细胞肿瘤, 上皮样滋养细胞肿瘤, 中间型滋养细胞

Abstract:

Epithelioid trophoblastic tumor（ETT）is a rare tumor which originates from the chorionic intermediate trophoblast.It occurs mostly in women of childbearing age，especially after full-term pregnancy.The clinical manifestation of ETT is similar to that of placental site trophoblastic tumor（PSTT）.About 70% of ETT patients have the complaint of vaginal bleeding，and moderate up-regulation of serum human chorionic gonadotropin （hCG） levels is widely found.Surgery is the preferred option for the treatment of ETT，and the effect of chemotherapy remains controversial.Patients without metastasis have a favourable prognosis，but metastasis comes with a very poor prognosis.

Key words: gestational trophoblastic neoplasm, epithelioid trophoblastic tumor, intermediate trophoblast

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