上皮样滋养细胞肿瘤的诊治
Diagnosis and treatment of epithelioid trophoblastic tumor
上皮样滋养细胞肿瘤(epithelioid trophoblastic tumor,ETT)起源于绒毛膜型中间型滋养细胞,非常罕见,生育期年龄妇女多见,常继发于足月妊娠,临床表现与胎盘部位滋养细胞肿瘤(placental site trophoblastic tumor,PSTT)相似,约70%出现阴道流血,血hCG水平中度升高。手术是ETT主要的治疗手段,化疗效果目前仍存在争议。无转移者预后良好,但一旦转移预后极差。
Epithelioid trophoblastic tumor(ETT)is a rare tumor which originates from the chorionic intermediate trophoblast.It occurs mostly in women of childbearing age,especially after full-term pregnancy.The clinical manifestation of ETT is similar to that of placental site trophoblastic tumor(PSTT).About 70% of ETT patients have the complaint of vaginal bleeding,and moderate up-regulation of serum human chorionic gonadotropin (hCG) levels is widely found.Surgery is the preferred option for the treatment of ETT,and the effect of chemotherapy remains controversial.Patients without metastasis have a favourable prognosis,but metastasis comes with a very poor prognosis.
妊娠滋养细胞肿瘤 / 上皮样滋养细胞肿瘤 / 中间型滋养细胞
gestational trophoblastic neoplasm / epithelioid trophoblastic tumor / intermediate trophoblast
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