The clinical data of a child with parenteral infection of rotavirus admitted to Guangzhou Women and Children’s Medical Center，Guangzhou Medical University in January 2023 were retrospectively analyzed，and the characteristics of the disease and diagnosis and treatment experience were analyzed based on the literature.A 1-year-old male child had vomiting，changes in stool traits and fever at onset，and he rapidly presented with convulsions，consciousness disturbance and shock. Cranial CT suggested acute necrotizing encephalopathy. Stool specimens were tested and showed weakly positive for rotavirus. CSF and blood samples were subjected to metagenomic next-generation sequencing （mNGS）and rotavirus was detected，Rotavirus infection was detected by local histopathology（hematoxylin-eosin staining，HE）in several organs，suggesting that rotavirus could cause damage to various organs through viremia. We should be alert to parenteral infection after rotavirus infection.

child, rotavirus, rotavirus parenteral infection, death

回顾性分析肠内及肠外多器官感染轮状病毒1例患儿临床资料，并结合文献分析疾病特点及诊治经验。患儿男，1岁，以呕吐、大便性状改变、发热起病，迅速出现惊厥、意识障碍及休克等多器官损伤，头颅计算机断层扫描示急性坏死性脑病，粪标本检测轮状病毒呈阳性，脑脊液及血液样本经宏基因组二代测序检测出轮状病毒，多个器官局部组织病理检测均存在轮状病毒感染，提示轮状病毒可以通过病毒血症引起各器官损伤，病情进展迅速、预后差，轮状病毒感染引起肠外表现需要引起临床医生高度重视。

儿童, 轮状病毒, 轮状病毒肠外感染, 死亡