Abstract: Objective    To summarize the gastroscopic findings of pediatric eosinophilic gastrointestinal diseases（EGIDs）with upper gastrointestinal tract involvement. Methods    Collect and analyze the results of gastroscopy in children with EGIDs with upper gastrointestinal tract involvement admitted to the Gastroenterology Department，Beijing Children's Hospital，Capital Medical University from January 1，2016 to December 31，2022. Results    A total of 121 children with EGIDs were included in the study（89 males and 32 females）. There were 31 cases（25.62%） of esophageal involvement，39 cases（32.23%）of gastric involvement，and 85 cases（70.25%） of duodenum involvement.Common abnormalities in patients with esophageal involvement were mucosal roughness（32.26%），hyperemia and edema（25.81%），rings（9.68%），erosion（9.68%），and erythema（9.68%），and gastroscopy was normal in 45.16% of patients.Gastric mucosal hyperemia and edema（100%），mottling（71.79%），erythema（25.64%），mucous lake turbidity or bile dyed（23.08%），hemorrhage（20.51%），erosion（15.38%），mucosal roughness（15.38%），and ulcers（12.82%） were observed in gastric involvement 
patients. Gastroscopy was normal in 28.24% of patients with duodenal involvement，the common abnormalities of whom were mucosal hyperemia and edema（58.82%），ulcer（31.76%），white exudates（23.53%），erythema（22.35%），roughness（22.35%），and erosion（15.29%），etc. The incidence of ulcers in children with duodenal involvement was higher than that in children with gastric involvement（χ2=5.011，P<0.05），while hemorrhage was more common in the stomach（χ2=5.940，P<0.05）. Conclusion    The gastroscopic manifestations of pediatric EGIDs are non-specific.Mucosal roughness，hyperemia and edema and rings are observed in patients with esophageal involvement. There is mucosal hyperemia and edema，mottling and erythema in patients with gastric involvement. In children with duodenal involvement，the common abnormalities are mucosal hyperemia and edema，ulcers，white exudates and erythema.About half of children with esophageal involvement and a quarter of children with duodenal involvement have normal gastroscopic findings.

Key words: eosinophilic gastrointestinal diseases, gastroscopy, pediatric

摘要： 目的    总结上消化道受累的儿童嗜酸性粒细胞性胃肠道疾病（eosinophilic gastrointestinal diseases，EGIDs）的胃镜表现，为儿童EGIDs的诊断提供经验。方法    收集并分析2016-01-01—2022-12-31首都医科大学附属北京儿童医院消化科就诊的上消化道受累的EGIDs患儿初次诊断时胃镜检查结果。结果    共纳入121例上消化道受累的EGIDs患儿（男89例、女32例），食管受累者31例（25.62%），胃部受累者39例（32.23%），十二指肠受累者85例（70.25%）。食管受累者中常见的异常为黏膜粗糙（32.26%）、充血水肿（25.81%）、环状改变（9.68%）、糜烂（9.68%）、黏膜红斑（9.68%），胃镜下无异常的占45.16%。胃部受累者可见胃黏膜充血水肿（100%）、胃黏膜花斑样（71.79%）、黏膜红斑（25.64%）、胃底黏液池浑浊或胆染（23.08%）、出血斑或咖啡斑（20.51%）、糜烂（15.38%）、黏膜粗糙（15.38%）及溃疡（12.82%）。十二指肠受累者常见异常为黏膜充血水肿（58.82%）、溃疡（31.76%）、白苔（23.53%）、红斑（22.35%）、粗糙（22.35%）、糜烂（15.29%）等，胃镜下未见异常的为28.24%。十二指肠受累者溃疡发生率高于胃部受累者（χ2=5.011，P<0.05），而出血样改变更常见于胃部（χ2=5.940，P<0.05）。结论    儿童EGIDs胃镜表现缺乏特异性。食管受累者可见黏膜粗糙、充血水肿、环状改变等；胃部受累者可见黏膜充血水肿、花斑样、黏膜红斑等，而十二指肠受累常见异常为黏膜充血水肿、溃疡、白苔、黏膜红斑等。约半数食管受累和1/4十二指肠受累的EGIDs患儿胃镜下表现无异常。

关键词: 嗜酸性粒细胞性胃肠道疾病, 胃镜检查, 儿童