Abstract:

Discussed the importance of multi-center clinical research and multidiscipline term model for childhood malignant solid tumor. The results of Adolescent and childhood malignant germ cell tumor，vinblastine and anaplastic large cell lymphoma, maintenance therapy for osteosarcoma were introduced as samples. Radiotherapy，stem cell transplantation and target therapy were discussed in comprehensive therapies of malignant solid tumor. The current situation and of China was presented. We needs further improving in this field.

Key words: solid-tumor, multi-center, multi-discipline, therapy, child

摘要：

国际儿童实体瘤多中心协作研究、多学科协同工作模式对儿童实体瘤预后进步有重要影响，以青少年/儿童恶性生殖细胞瘤、长春花碱对儿童间变大细胞淋巴瘤预后影响、骨肉瘤随机分组研究维持治疗的有效性多中心临床研究结果为例进行探讨。对放疗、造血干细胞移植、靶向治疗等在儿童实体瘤儿童肿瘤综合治疗中地位作用进行介绍。同时讨论了我国儿童实体瘤诊治现状和加以改善的期望。

关键词: 实体瘤, 多中心, 多学科, 治疗, 儿童