中国实用儿科杂志

中国实用儿科杂志 ›› 2024, Vol. 39 ›› Issue (5): 346-350.DOI: 10.19538/j.ek2024050607

• 专题笔谈 • 上一篇    下一篇

早产、低出生体重儿坏死性小肠结肠炎的外科干预研究进展

  

  1. 1.山西省儿童医院  外科，山西  太原  030009；2.山西医科大学儿科系，山西  太原  030001 
  • 出版日期:2024-05-06 发布日期:2024-05-09
  • 通讯作者: 任红霞，电子信箱：renhongxia100@sina. com
  • 基金资助:
    山西省儿童医院院内基金项目（No. 2023002） 

Research progress on surgical intervention of necrotizing enterocolitis in premature and low birth weight infants

  1. *Surgery Department of Shanxi Children's Hospital，Taiyuan  030009，China
  • Online:2024-05-06 Published:2024-05-09

摘要： 坏死性小肠结肠炎（necrotizing enterocolitis，NEC）是多发于早产、低出生体重儿的一种常见的胃肠道疾病，表现为小肠、结肠发生肠黏膜、肌层甚至肠壁全层弥散性或局限性坏死，也是早产、低出生体重儿死亡的主要原因之一。随着医学的进步尤其围产医学、重症医学的发展，早产、低出生体重儿的存活率大大提高，与之相应的早产、低出生体重儿NEC发病率也逐渐提高。NEC若保守治疗未能控制，则需及时外科干预。新生儿NEC的手术指征、治疗时机存在争议，对于早产、低出生体重儿更具分歧。该文重点阐述需要外科干预的早产、低出生体重儿NEC的临床特点、手术指征以及手术方式。

关键词: 坏死性小肠结肠炎, 早产儿, 低出生体重儿, 外科干预 

Abstract: Necrotizing enterocolitis（NEC） is a common gastrointestinal disease that occurs mostly in premature infants and low birth weight infants. It is manifested as diffuse or limited necrosis of intestinal mucosa，muscle layer or even all intestinal wall in the small intestine and colon. It is also one of the main causes of death in premature infants and low birth weight infants. With the progress of medicine，especially the development of perinatal medicine and intensive care medicine，the survival rate of premature infants and low birth weight infants has been greatly increased，and the corresponding incidence of NEC in premature and low birth weight infants has also increased. If NEC cannot be controlled by conservative treatment，timely surgical intervention is required. The surgical indication and treatment timing of neonatal necrotizing enterocolitis are controversial，more so for premature and low birth weight infants. This review focuses on the clinical features，surgical indications and operation methods of premature and low birth weight infants with NEC requiring surgical intervention. 

Key words: necrotizing enterocolitis, premature infant, low birth weight infant, surgical intervention