儿童, 轮状病毒, 轮状病毒肠外感染, 死亡

The clinical data of a child with parenteral infection of rotavirus admitted to Guangzhou Women and Children’s Medical Center，Guangzhou Medical University in January 2023 were retrospectively analyzed，and the characteristics of the disease and diagnosis and treatment experience were analyzed based on the literature.A 1-year-old male child had vomiting，changes in stool traits and fever at onset，and he rapidly presented with convulsions，consciousness disturbance and shock. Cranial CT suggested acute necrotizing encephalopathy. Stool specimens were tested and showed weakly positive for rotavirus. CSF and blood samples were subjected to metagenomic next-generation sequencing （mNGS）and rotavirus was detected，Rotavirus infection was detected by local histopathology（hematoxylin-eosin staining，HE）in several organs，suggesting that rotavirus could cause damage to various organs through viremia. We should be alert to parenteral infection after rotavirus infection.

child, rotavirus, rotavirus parenteral infection, death