关键词: 儿科重症, 儿童脓毒症, 儿科急性呼吸窘迫综合征, 精准治疗, 诊治进展

Abstract: In recent years，with the innovation in diagnostic technologies，evidence-based optimization of treatment strategies，and improvement in multidisciplinary collaboration models，notable advancements have been achieved in the field of pediatric critical care. This article systematically summarizes the latest research findings in recent years in diagnostic criteria，detection technologies，targeted therapy，and organ support for pediatric sepsis and pediatric acute respiratory distress syndrome（PARDS）. It places a particular focus on the application progress of blood purification technologies（CRRT，adsorption，plasma exchange） in sepsis and the evidence for individualized precision treatment with glucocorticoids. Furthermore，this article provides an in-depth analysis of the challenges encountered in current clinical practice，and prospects the future development directions including personalized medical treatment，intelligent diagnosis and treatment，and deepened multidisciplinary collaboration，aiming to provide references for clinical practice and scientific research exploration.

Key words: pediatric critical care, pediatric sepsis, pediatric acute respiratory distress syndrome（PARDS）, precision treatment, diagnosis and treatment progress