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Abstract: Adolescence is a critical period of development，characterized by rapid physical growth，sexual maturation，and the formation of behavioral and cognitive patterns. In recent years，there has been a sharp increase in the incidence of health issues among adolescents，including obesity，diabetes，hyperuricemia，cardiovascular and cerebrovascular diseases，and mental and behavioral problems. These are closely related to nutritional and metabolic abnormalities during puberty. Adolescent development is influenced by multiple factors，such as genetics，neuroendocrine，nutritional metabolism，and living environment. Among these，nutritional and metabolic interventions，along with lifestyle management，represent key modifiable factors. Therefore，systematic nutritional and metabolic screening，comprehensive assessment，and personalized interventions help to promote adolescent health. These measures hold significant clinical and public health importance in preventing and managing adolescent diseases and chronic conditions in adulthood.

Key words: adolescence, nutrition, obesity, psychiatric disorders, metabolic imbalance