中国实用儿科杂志

中国实用儿科杂志 ›› 2024, Vol. 39 ›› Issue (1): 47-50.DOI: 10.19538/j.ek2024010609

• 专题笔谈 • 上一篇    下一篇

益生元及后生元在儿科临床中的应用

  

  1. 苏州大学附属儿童医院，江苏  苏州  215003
  • 出版日期:2024-01-06 发布日期:2024-02-23
  • 通讯作者: 武庆斌，电子信箱：qingbin6638@163.com

Prebiotics and postbiotics in pediatric clinical application

  1. Children’s Hospital of Soochow University，Suzhou  215003，China
  • Online:2024-01-06 Published:2024-02-23

摘要： 益生元是能够被宿主微生物选择性利用从而赋予健康益处的底物。后生元是为宿主提供健康益处的无生命微生物和（或）其相关成分的制剂。尽管二者制剂成分不同，但是作用机制是益生元或后生元与肠道菌群相互作用后，赋予宿主健康益处。这对于儿童，尤其是生命早期的婴儿防治疾病和健康成长尤为重要。文章通过厘清益生元和后生元概念，讨论作用机制和儿科临床应用效果，有助于今后益生元和后生元在儿科临床研究和应用的深入开展。

关键词: 益生元, 后生元, 儿科, 临床应用

Abstract: Prebiotics are substrates that can be selectively utilized by host microorganisms to confer health benefits.Postbiotics are preparations of inanimate microorganisms and/or their related components that provide health benefits to the host. Although the ingredients of the two formulations are different，the mechanism of action is the interaction of prebiotics or postbiotics with the gut microbiota，which endows the host with health benefits.This is particularly important for children，especially for infant disease prevention and healthy growth in early childhood. This article aims to clarify the concepts of prebiotics and postbiotics，discuss their mechanisms of action，and evaluate their clinical application in pediatrics，which will contribute to the in-depth research and application of prebiotics and postbiotics in pediatrics in the future.

Key words: prebiotics, postbiotics, pediatrics, clinical applic-ation