关键词: 益生菌, 儿童, 肝胆疾病

Abstract:

Probiotics are live，nonpathogenic bacteria with the function of improving  the micro-environment and promoting the health of the host. The "gut-liver axis" shows that there is complexed relationship between the liver/gallbaldder and gut microbiota. Alterations of the type and amount of the micro-organisms in the intestinal tract can result in liver dysfunction due to the production of ammonia and endotoxin. Some studies have confirmed the positive influence of probiotic strains on the prevention and treatment of liver and biliary diseases in children，such as nonalcoholic fatty liver disease，cholestasis，cirrhosis，and liver transplantation. Probiotic therapy，as a safe，inexpensive and noninvasive treatment strategy，can alleviate and improve the  pathophysiological courses and symptoms of different types of liver and biliary diseases without obvious side effects，which has great prospect of application .

Key words: probiotics, child, liver and biliary disease