Acta Metallurgica Sinica

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Role of mTOR signaling pathway in the field of stomatology.

SHEN Jia-yuanLIU Yi   

  1. Fengtian Dental Clinic,School of Stomatology,China Medical University,Shenyang 110013,China
  • Online:2014-11-15 Published:2014-11-20

mTOR信号通路在口腔医学领域作用研究进展

沈家媛综述刘奕审校   

  1. 作者单位:中国医科大学附属口腔医院奉天门诊,辽宁省口腔医学研究所,沈阳110013
  • 通讯作者: 刘奕
  • 基金资助:

    辽宁省科学技术计划项目(2013225090)

Abstract:

Abstract:The mTOR (mammalian target of rapamycin),a serine/threonine protein kinase,which plays an important role in the proliferation of normal cells and is closely related to the growth of cancer cells,is the central regulator of the growth and differentiation of cells. The mTOR is involved in multiple signaling pathways,and plays an important role in the process of gene transcription, protein translation and ribosome synthesis. This article makes a summary on the role of mTOR signaling pathway in the field of stomatology.

Key words: mTOR, signal pathway, stomatology

摘要:

mTOR是一种丝氨酸/苏氨酸蛋白激酶,不仅在正常细胞的生长增殖中起着极其重要的作用,而且与癌细胞的生长密切相关,是细胞生长、分化的中心调控者。mTOR参与体内多条信号通路,并在基因转录、蛋白质翻译、核糖体合成等过程中发挥重要作用。本文对mTOR信号通路在口腔医学领域中的作用做一综述。

关键词: mTOR, 信号通路, 口腔医学

CLC Number: