Abstract:

 Chemokine stromal cell-derived factor-1（SDF-1）has characteristics of cell migration and is expected to be used in the field of oral tissue repair and regeneration. When the damage occurs in the body's tissues and organs，impaired cells secret and express SDF-1 and recruit bone marrow-derived stem cells or progenitor cells to the injured site，so as to promote the repair of damaged tissue by providing the new blood vessels and cells. This paper summarizes the effect of SDF-1 in oral tissue repair and the direction of future researches of the SDF-1.

Key words: stromal cell-derived factor-1, SDF-1；tissue repair；oral

摘要：

基质细胞衍生因子-1（SDF-1）因具有定向趋化多种细胞的特性，有望被应用于口腔组织修复再生领域。当机体组织器官发生损伤时，受损部位的细胞分泌表达SDF-1并募集骨髓源性的干细胞或祖细胞向损伤部位迁移，从而促进损伤部位新血管形成和组织细胞的代偿修复。本文就近年来有关SDF-1在口腔组织修复中的作用和应用研究做一综述。

关键词: 基质细胞衍生因子-1, 组织修复, 口腔