Acta Metallurgica Sinica

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  • Online:2018-12-15 Published:2019-01-09

维生素D、自噬与口腔疾病

王健吴倩胡新月杨雪牛丽唐晓琳   

  1. 中国医科大学口腔医学院·附属口腔医院牙周病科,辽宁  沈阳  110002
  • 基金资助:

    国家自然科学基金(81670999)

Abstract:

 Autophagy plays an important role in the evolution of eukaryotes. In the process of autophagy,the cell can provide nutrients and energy through the degradation of non-essential components of the cell to achieve the turnover of intracellular materials and to cope with transient stress. Autophagy is associated with a variety of oral diseases. Vitamin D can promote autophagy and actively participats in the regulation of immune and inflammatory responses. This article reviews the relationship among vitamin D,autophagy,and oral diseases.

Key words: Vitamin D, autophagy, oral diseases

摘要:

自噬在真核生物进化过程中起着重要作用。在自噬过程中,细胞可通过降解自身的非必需成分来提供营养和能量,从而实现胞内物质转化和应对短暂的生存压力。自噬与多种口腔疾病关系密切。维生素D是一种重要的自噬激活因子,积极参与调节免疫和炎症反应。文章对维生素D、自噬与口腔疾病的关系做一综述。

关键词: 维生素D, 自噬, 口腔疾病