Abstract:

With the discovery of dental stem cells and the development of tissue engineering，tissue engineering technology based on stem cells provides a new direction and strategy for the treatment of dental pulp disease. In this article，we review the current studies of dental stem cells，including dental pulp stem cells，apical papilla stem cells and stem cells from exfoliated deciduous teeth，in pulp-dentin regeneration. The use of stem cell sheets and exosomes derived from dental stem cells are discussed as well.

Key words: dental stem cells, pulp-dentin regeneration, tissue engineering

摘要：

随着牙源性干细胞的发现和组织工程技术的发展，以干细胞为基础的组织工程技术为牙髓病的治疗提供了新的方向和思路。文章将对牙髓干细胞、根尖牙乳头干细胞、脱落乳牙干细胞等牙源性干细胞、干细胞膜片以及干细胞来源的外泌体应用于牙髓牙本质再生的研究进展做一综述。

关键词: 牙源性干细胞, 牙髓牙本质再生, 组织工程