Abstract: Objective　To evaluate the diagnostic value of lung ultrasound for neonatal pneumonia by Meta-analysis.Methods　PubMed，Cochrane library，Embase，CNKI and Wanfang Database were searched from database establishment to September 2018 to gather articles according to the inclusion and exclusion criteria of diagnostic research. A total of 907 studies were retrieved. Eight studies were selected for analysis. QUADAS2 was used to evaluate the quality of articles included. Heterogeneity was assessed by using Q and I 2 statistics. Meta-Disc 1.4 software was applied for the statistical analysis to evaluate the diagnostic value of lung ultrasound for neonatal pneumonia. Results　A total of 8 articles involving 1078 cases were included. Random effect model was adopted for statistical analysis. The pooled sensitivity was 0.96（95%CI：0.95-0.98）；the pooled specificity was 0.98（95%CI：0.95-0.99）；the pooled positive likelihood ratio was 19.52（95%CI：5.00-76.15）；the pooled negative likelihood ratio was 0.04（95%CI：0.01-0.16）；the pooled odds ratio was 565.45（81.80-3908.58）；the area under SROC was 0.9950. Conclusion　The sensitivity and specificity of lung ultrasound in the diagnosis of neonatal pneumonia are higher than X-ray. Considering the features of being easy，readily availability，low cost，and being free from radiological hazards，current evidence supports lung ultrasound as an imaging alternative for the diagnosis of neonatal pneumonia.

Key words: ultrasound, neonatal pneumonia, diagnosis, Meta-analysis

摘要： 目的　采用 Meta 分析方法来评价肺脏超声对新生儿肺炎的诊断价值。方法　检索PubMed、Cochrane library、Embase、CNKI 和万方数据库，按照诊断性试验的纳入和排除标准，获取符合本研究要求的文献，检索时间为建库至 2018年9月。共检索到907篇文献，选取其中8篇进一步分析，并对文献质量进行QUADAS2标准评价，采用Q检验和I 2统计量进行异质性检验，采用 Meta-Disc 1.4 软件进行统计学分析，评价肺脏超声对新生儿肺炎的诊断价值。 结果　共纳入8篇文献、1078例。采用随机效应模型对纳入的研究进行统计分析，合并敏感度为0.96（95%CI：0.95～0.98），合并特异度为0.98（95%CI：0.95～0.99），合并阳性似然比为19.52（95%CI：5.00～76.15），合并阴性似然比为0.04（95%CI：0.01～0.16），合并诊断优势比为565.45（81.80～3908.58），拟合ROC 曲线下面积0.9950。结论　肺脏超声诊断新生儿肺炎的敏感度和特异度较X线高。鉴于其相对容易操作、实时可用、低成本和无电离辐射，目前的证据支持超声作为新生儿肺炎诊断的替代手段。

关键词: 超声, 新生儿肺炎, 诊断, Meta 分析